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Mamit-tRNA specifications


Unique identifier OMICS_16437
Name Mamit-tRNA
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes


  • person_outline Catherine Florentz

Publication for Mamit-tRNA

Mamit-tRNA citations


Mitochondrial mutations drive prostate cancer aggression

Nat Commun
PMCID: 5610241
PMID: 28939825
DOI: 10.1038/s41467-017-00377-y

[…] ontrol region were obtained from Pathogenicity scores from MutPred, PolyPhen-2 and SiteVar were obtained from the MToolBox output. Mutations in tRNA genes were compared to the Mamit-tRNA database.We chose to a threshold of 0.2 ∆HF in order to balance removing false positives without excluding a large number of mtSNVs unnecessarily (Supplementary Fig. ). As part of this asse […]


A comprehensive collection of annotations to interpret sequence variation in human mitochondrial transfer RNAs

BMC Bioinformatics
PMCID: 5123245
PMID: 28185569
DOI: 10.1186/s12859-016-1193-4

[…] g rRNAs, respectively. All the tracks were produced using the revised Cambridge Reference Sequence, rCRS (GenBank: J01415.2), as reference sequence.Additional information from MITOMAP [], ClinVar [], Mamit-tRNA [] dbSNP [] and OMIM [] databases were shown, when available, for all the four tracks, as well as variability data from HmtDB database [] and conservation scores from UCSC Genome Browser [, […]


Mitochondrial Sequence Variation in African American Primary Open Angle Glaucoma Patients

PLoS One
PMCID: 3798711
PMID: 24146900
DOI: 10.1371/journal.pone.0076627

[…] PolyPhen-2. The third, m.12266A>G, is located within the 5'-acceptor end of the MT-TL2 tRNA leucine gene. This A>G transition has been observed in another primate and other organisms according to the Mamit-tRNA database [] (, so is also unlikely to be pathogenic.For the population as a whole (n = 44) the proportion with novel transversions was 2.3% (95% confidence in […]


Functional Recurrent Mutations in the Human Mitochondrial Phylogeny: Dual Roles in Evolution and Disease

Genome Biol Evol
PMCID: 3673625
PMID: 23563965
DOI: 10.1093/gbe/evt058

[…] s,” which are RNA structures that are composed of two helical segments at least, connected by single-stranded regions or loops (). For analysis of tRNA genes, we retrieved the RNA structures from the Mamit-tRNA website (, last accessed April 22, 2013), while rRNA gene structures were retrieved from the CRW website (, last accessed April 22, 2013). Fo […]


Mitochondrial DNA sequence variation in Finnish patients with matrilineal diabetes mellitus

BMC Res Notes
PMCID: 3434112
PMID: 22780954
DOI: 10.1186/1756-0500-5-350
call_split See protocol

[…] cing in both directions at least twice from different PCR products. Previously reported pathogenic mutations were identified according to Mitomap. Base conservation in tRNA genes was determined using Mamit tRNA: Compilation of Mammalian mitochondrial tRNA genes[] and conservation of other mtDNA-encoded genes using the GiiB-JST mtSAP evaluation […]


Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code

Biol Direct
PMCID: 2630981
PMID: 19091122
DOI: 10.1186/1745-6150-3-53
call_split See protocol

[…] is of glycine tRNA gene sequences from mitochondria and chloroplasts used the Compilation of tRNA Genes section of the Compilation of tRNA sequences and sequences of tRNA genes [] in conjunction with Mamit-tRNA: Compilation of mammalian mitochondrial tRNA genes [], which currently contains 3064 tRNA gene sequences from 150 fully sequenced genomes available on GenBank database (NCBI).All sequences […]


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Mamit-tRNA institution(s)
Architecture et Réactivité de l’ARN, Université Louis Pasteur de Strasbourg, CNRS, IBMC, Strasbourg, France; ULP-Multimédia, Université Louis Pasteur, Strasbourg, France
Mamit-tRNA funding source(s)
This work was funded by CNRS, Université Louis Pasteur, Association Francaise contre les Myopathies (AFM), and EC contract FP5 RTD QLG2-CT-00660.

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