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|Alternative name||Mammalian Phenotype Enrichment Analysis|
|Interface||Web user interface|
|Restrictions to use||None|
- person_outline Ben-Yang Liao
Publication for Mammalian Phenotype Enrichment Analysis
Comparative Genomics Reveals Accelerated Evolution in Conserved Pathways during the Diversification of Anole Lizards
[…] ed genes in each species to potential phenotypes, we examined statistically enriched GO categories as above, and tested for enrichment of mouse phenotypes using the gene IDs of the human orthologs in MamPhEA ().In anoles, limb morphology is related to locomotor differences and ecological niche adaptation among sympatric species (); therefore, we predict strong selective pressure on limb structure […]
Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis
[…] O terms associated with developmental processes, while upregulated genes, representing negative targets, were enriched for terms associated with mitosis, cell cycle regulation and metabolism (Fig. ). Mammalian phenotype enrichment analysis (MamPhEA) further demonstrated that MafB-regulated genes in retinal ECs were associated with phenotypes such as abnormal vasculature morphology, abnormal vascul […]
Evolutionary trajectories of snake genes and genomes revealed by comparative analyses of five pacer viper
[…] ired PSGs with the free-ratio model dN/dS>1 at the focal lineage. For the identified RSGs and PSGs, we used their mouse orthologs' mutant phenotype information and performed enrichment analyses using MamPhEA. Then we grouped the enriched MP terms by different tissue types. […]
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