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MAnorm

A simple and effective method for quantitative comparison of ChIP-Seq data sets describing transcription factor binding sites and epigenetic modifications. The quantitative binding differences inferred by MAnorm showed strong correlation with both the changes in expression of target genes and the binding of cell type-specific regulators.

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MAnorm classification

MAnorm specifications

Software type:
Package/Module
Restrictions to use:
None
Programming languages:
MATLAB, R
Stability:
Stable
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
Computer skills:
Advanced
Maintained:
Yes

MAnorm distribution

versioning

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No versioning.

Credits

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Publications

Institution(s)

Departments of Pediatric Oncology and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA, Division of Pediatric Hematology-Oncology, The Karp Family Research Laboratories, Children's Hospital, Boston, MA, USA and Division of Cell and Molecular Biology, Department of Biology, Boston University, Boston, MA, USA

Link to literature

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