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MAPPP computational protocol

MAPPP specifications

Information


Unique identifier OMICS_05743
Name MAPPP
Alternative names MHC-I Antigenic Peptide Processing Prediction, FRAGPREDICT
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Hans Mollenkopf <>

Publication for MHC-I Antigenic Peptide Processing Prediction

MAPPP IN pipelines

 (9)
2018
PMCID: 5773588
PMID: 29348555
DOI: 10.1038/s41598-018-19456-1

[…] dataset. netctl was selected to predict the ctl epitopes because of its higher prescient execution on all execution parameters as compared to the recently developed servers namely mhc-pathway, mappp, and epijen. all the salivary protein sequences were submitted in the fasta format to predict the ctl epitope at the threshold score of 0.75 (default). those epitopes having a combined score […]

2017
PMCID: 5450251
PMID: 28584450
DOI: 10.6026/97320630013094

[…] rank, 0.5 and 2 respectively was used in our study as in previous reports on other analytical approaches. strong binders alone were selected and used for further analysis., this was predicted using mappp (mhc-i antigenic peptide processing prediction) program [20]. the program generates a probability for the cleavage of each possible peptide from a protein by the proteasome in the cell […]

2017
PMCID: 5450251
PMID: 28584450
DOI: 10.6026/97320630013094

[…] cleavage of each possible peptide from a protein by the proteasome in the cell and the probability is based on a statistic-empirical method. the algorithms in the program were earlier implemented in fragpredict. minimum possibility for cleavage after a single residue and for cleavage of a fragment was set to default value of 0.5., to predict the candidate epitope(s) based on the processing […]

2017
PMCID: 5602290
PMID: 28943728
DOI: 10.6026/97320630013231

[…] amur) causing hfrs. the epitopes that bind to class i hla supertypes that is also cleaved only at the flanking regions by human proteasomes, binding to tap efficiently was identified by the programs mappp and tappred respectively. this study enabled the prediction of mhc class i binding t- cell epitopes from hantaviruses towards development of a designer peptide vaccine., all available complete […]

2017
PMCID: 5602290
PMID: 28943728
DOI: 10.6026/97320630013231

[…] (nonamer) was derived with the default threshold for strong binding and weak binding in terms of percent rank. strong binders alone were selected and used for further analysis as shown below:, mhc-i antigenic peptide processing prediction (mappp) program [17] was used to predict proteasomal cleavage. the program generates a probability for the cleavage of each possible peptide […]

MAPPP institution(s)
University of Ulm, Department of Theoretical Computer Science, Ulm, Germany

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