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Mascot Distiller specifications


Unique identifier OMICS_24182
Name Mascot Distiller
Software type Application/Script
Interface Graphical user interface
Restrictions to use License purchase required
Input data A mass spectrometry data file.
Output format MGF,DTA
Operating system Windows
Computer skills Medium
Version 2.6.3
Stability Stable
Mascot Server
Free trial Yes
Maintained Yes




No version available


  • person_outline Mascot Distiller Team

Mascot Distiller citations


Identification of N Terminally Truncated Derivatives of Insulin Analogs Formed in Pharmaceutical Formulations

Pharm Res
PMCID: 5956049
PMID: 29770892
DOI: 10.1007/s11095-018-2426-1

[…] zer calibration mixture provided by Applied Biosystems. Samples were spotted onto a 384 Opti-TOF MALDI plate and analyzed. Data Explorer Software, Version 4.9 was applied to process acquired spectra. Mascot Distiller Software (version, Matrix Science) was employed to predict fragment ions from given peptide sequences and overlay them on the acquired MS/MS spectra. […]


GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer

PMCID: 5955133
PMID: 29774096
DOI: 10.18632/oncotarget.24796

[…] ested with trypsin. Generated peptides were analyzed in a nanoLC-MS/MS system (Q-TOF Synapt G2 MS; Waters). The peptide and protein identification was performed using MASCOT search engine through the MASCOT Distiller interface (Matrix Science). The queried database was the Swiss-Prot. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE [] partn […]


Stability of Antiradical Activity of Protein Extracts and Hydrolysates from Dry Cured Pork Loins with Probiotic Strains of LAB

PMCID: 5946306
PMID: 29690547
DOI: 10.3390/nu10040521

[…] anoACQUITY Symmetry C18 Waters 186003545) column using a gradient of acetonitrile (0−35% AcN over 180 min) in the presence of 0.05% formic acid at a flow rate of 250 nL/min. The data was processed by Mascot Distiller and Mascot Search (Matrix science, London, UK) and then compared to the Uniprot database. The search parameters for precursor ions and mass tolerance products were 10 ppm and 0.1. Da. […]


Sequence, genome organization, annotation and proteomics of the thermophilic, 47.7 kb Geobacillus stearothermophilus bacteriophage TP 84 and its classification in the new Tp84virus genus

PLoS One
PMCID: 5889276
PMID: 29624616
DOI: 10.1371/journal.pone.0195449

[…] ly coupled to the ion source of the spectrometer working in the regime of data dependent MS to MS/MS switch (Orbitrap Velos mass spectrometer-Thermo Electron Corp.). The raw data were processed using Mascot Distiller followed by Mascot Search against the TP-84 proteins database. Peptides with a Mascot Score exceeding the 5% False Positive Rate threshold and with a Mascot Score exceeding 148 were c […]


Cold and Heat Stress Diversely Alter Both Cauliflower Respiration and Distinct Mitochondrial Proteins Including OXPHOS Components and Matrix Enzymes

Int J Mol Sci
PMCID: 5877738
PMID: 29547512
DOI: 10.3390/ijms19030877

[…] ctrometer working in the regime of data dependent MS to MS/MS switch. A blank run ensuring lack of cross contamination from previous samples preceded each analysis.Acquired raw data were processed by Mascot Distiller followed by Mascot search (Matrix Science, London, UK, 8-processor on-site license) against NCBInr (version 20100203) with taxonomy restricted to Viridiplantae. Search parameters for […]


Low Bioavailability and High Immunogenicity of a New Brand of E. colil Asparaginase with Active Host Contaminating Proteins

PMCID: 5952248
PMID: 29550241
DOI: 10.1016/j.ebiom.2018.03.005
call_split See protocol

[…] The raw data from MS Bioworks were processed using Mascot Distiller 2.3 and the resulting MGF file was used in Mascot server 2.3 (Matrix Science Ltd) to search for non-specific cleavages using the same parameters described above. The scoring function […]


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Mascot Distiller institution(s)
Matrix Science Inc, Boston, MA, USA

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