MaxLink specifications

Information


Unique identifier OMICS_07800
Name MaxLink
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C++
Computer skills Advanced
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Versioning


No version available

Maintainer


  • person_outline Dimitri Guala

Information


Unique identifier OMICS_07800
Name MaxLink
Interface Web user interface
Restrictions to use None
Programming languages C++
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Dimitri Guala

MaxLink citations

 (2)
library_books

A large scale benchmark of gene prioritization methods

2017
Sci Rep
PMCID: 5399445
PMID: 28429739
DOI: 10.1038/srep46598

[…] The relationship between TPR and FPR for the FPR range of particular interest in gene prioritization, i.e. typically up to an FPR of 0.1, is depicted in ROC curves(). Superior performance for MaxLink across all specificity ranges and ontologies compared to the other tools was apparent both from the ROC curves and the corresponding pAUCs for the FPR up to 0.02(). What also became apparent w […]

library_books

HGCS: an online tool for prioritizing disease causing gene variants by biological distance

2014
BMC Genomics
PMCID: 4051124
PMID: 24694260
DOI: 10.1186/1471-2164-15-256

[…] to the core gene associated with the patient’s disease. We then compared the performance, interface and functions of the HGCS with those of two other state-of-the-art methods: (i) FunCoup, using the MaxLink interface, which ranks top interactors, and (ii) HumanNet, which ranks by top subnetworks [,]. In both FunCoup and HumanNet, we added the relevant core genes to the analyses, and chose the fir […]

MaxLink institution(s)
Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

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