McGenus specifications


Unique identifier OMICS_09267
Name McGenus
Interface Web user interface
Restrictions to use None
Input data RNA sequence
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Cristian Micheletti

Publication for McGenus

McGenus citations


Folding behavior of a T shaped, ribosome binding translation enhancer implicated in a wide spread conformational switch

PMCID: 5336357
PMID: 28186489
DOI: 10.7554/eLife.22883.019

[…] the most resistance to pulling and opened last. The parallel orientation of H4a/Ψ3 with respect to the direction of pulling increased its stability beyond what the free energy calculations (Mfold and McGenus) would suggest, again, in agreement with another OT pseudoknot unfolding study ().A sample SMD-simulated sequence of unfolding events is illustrated in and shown in the Supplementary SMD tra […]


Identification of consensus binding sites clarifies FMRP binding determinants

Nucleic Acids Res
PMCID: 5001617
PMID: 27378784
DOI: 10.1093/nar/gkw593

[…] ing complexes were found to bind to a KH domain-containing truncation of FMRP with high affinity (). We therefore asked whether FCBS sequences are enriched for putative kissing complexes. We used the McGenus algorithm () to predict pseudoknot folds that could be formed by each FCBS sequence and then assessed those folds for kissing complex structures similar to those previously found to bind FMRP. […]

McGenus institution(s)
Institut de Physique Théorique, CEA Saclay, CNRS URA 2306, Gif-sur-Yvette, France; SISSA, Scuola Internazionale Superiore di Studi Avanzati and CNR-IOM Democritos, Trieste, Italy

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