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mCluster specifications


Unique identifier OMICS_05374
Name mCluster
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline mCluster

Publication for mCluster

mCluster citations


Local Adaptation in European Firs Assessed through Extensive Sampling across Altitudinal Gradients in Southern Europe

PLoS One
PMCID: 4938419
PMID: 27392065
DOI: 10.1371/journal.pone.0158216

[…] iation showed a clear hierarchical genetic structure into clusters (K = 2) and sub-clusters (K = 4), as further confirmed by decreasing estimates of genome-wide parameters across geographical scales (μCluster> μSubCluster> μElev). This observation was concordant with a classical ‘isolation-by-distance’ model, in which the extent of neutral genetic differentiation increases with geographic distance […]


Exploiting topic modeling to boost metagenomic reads binning

BMC Bioinformatics
PMCID: 4402587
PMID: 25859745
DOI: 10.1186/1471-2105-16-S5-S2

[…] As in MCluster [], we use the SKWIC algorithm to cluster the vectorized metagenomic reads. SKWIC is a variant of the classical K-means method with automatic feature weighting mechanism []. It tries to minim […]


Assessment of computational methods for predicting the effects of missense mutations in human cancers

BMC Genomics
PMCID: 3665581
PMID: 23819521
DOI: 10.1186/1471-2164-14-S3-S7

[…] igas (Research Programme on Biomedical Informatics Barcelona) for helpful discussions. Special thanks go to Slaton Lipscomb (Genentech) for our compute cluster and Peng Yue (Genentech) for support of mCluster. […]


Simulation of Arrhythmogenic Effect of Rogue RyRs in Failing Heart by Using a Coupled Model

PMCID: 3465912
PMID: 23056145
DOI: 10.1155/2012/183978

[…] arameter of Ca2+ release events, and K mj is cytoplasmic Ca2+ sensitivity parameter of RyR clusters or rogue RyR channels. In our simulation work, K mrogue was always set to be of the same value as K mcluster; thus K m was used to represent the value of K mcluster and K mrogue.In this study, the simulation of subcellular Ca2+ handling was performed on the longitudinal section of a cardiac myocyte […]


Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences

Nucleic Acids Res
PMCID: 2655687
PMID: 19139068
DOI: 10.1093/nar/gkn1085

[…] server (A.F.A. Smit, R. Hubley and P. Green; The coordinates of ChIP and random sequences were mapped onto the human chromosomes using the ChromoMapper program ( (). S/MAR-specific and short oligomeric motifs were inspected using MAR-Wiz ( () and RSAT web-tools (http […]

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mCluster institution(s)
Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA; Department of Biostatistics, Genentech Inc., South San Francisco, CA, USA

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