An approach for studying the impact of missense mutations in proteins. mCSM, which relies on graph-based signatures, was successfully applied and evaluated in different predictive tasks and was shown to outperform earlier methods.
An approach for studying the impact of missense mutations in proteins. mCSM, which relies on graph-based signatures, was successfully applied and evaluated in different predictive tasks and was shown to outperform earlier methods.
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Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK