Main logo
?
tutorial arrow
×
Submit new tools
Share tools covering the current topic. Provide easy-to-follow guidelines to improve their usability.
Share new tools with the community
Sign up for free to promote the availability of bioinformatics tools

Multiple domain alignment software tools | Protein comparison analysis

The best currently available methods to study domain arrangements are classical multiple sequence alignment (MSA) methods. However, these alignment methods usually do not explicitely take domain arrangements into account and therefore do not…
CDTree
Desktop

CDTree Conserved Domain Tree

Enables users of the CDD (conserved domain database) resource to examine…

Enables users of the CDD (conserved domain database) resource to examine curated hierarchies. CDD and CDTree used in concert, serve as a powerful tool in protein classification, as they allow users…

Dialign-Pfam
Web

Dialign-Pfam

Identifies possible domains in protein sequences by scanning the input…

Identifies possible domains in protein sequences by scanning the input sequences using HMMER against PFAM database. Dialign-Pfam then uses this information to align protein sequences using Dialign.

MDAT
Desktop

MDAT Multiple Domain Alignment Tool

A multiple domain alignment program that aligns multiple domain arrangements.…

A multiple domain alignment program that aligns multiple domain arrangements. MDAT extends earlier programs which perform pairwise alignments of domain arrangements. MDAT uses a domain similarity…

COBALT
Desktop
Web

COBALT

A constraint based alignment tool that implements a general framework for…

A constraint based alignment tool that implements a general framework for multiple alignment of protein sequences. COBALT finds a collection of pairwise constraints derived from database searches,…

FlowerPower
Web
Desktop

FlowerPower

A package for the identification of global homologs as a precursor to…

A package for the identification of global homologs as a precursor to structural phylogenomic analysis. FlowerPower employs an iterative approach to clustering sequences. This tool identifies…

MetaDomain
Desktop

MetaDomain

Provides a protein domain classification for short reads generated by…

Provides a protein domain classification for short reads generated by next-generation sequencing technologies. MetaDomain uses relaxed position-specific score thresholds to align more reads to a…

Information

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.