A manually curated catalog of molecular genetic data relating to genes involved in melanoma. The main purpose of this database is to establish a network of melanoma related genes and to facilitate the mechanistic study of melanoma tumorigenesis. The entries describing the relationships between melanoma and genes in the current release were manually extracted from PubMed abstracts, which contains cumulative to date 527 human melanoma genes (422 protein-coding and 105 non-coding genes). Each melanoma gene was annotated in seven different aspects (General Information, Expression, Methylation, Mutation, Interaction, Pathway and Drug). In addition, manually curated literature references have also been provided to support the inclusion of the gene in MGDB and establish its association with melanoma. MGDB has a user-friendly web interface with multiple browse and search functions.
Institute of Health Sciences, School of Computer Science and Technology, Anhui University, Hefei, Anhui, China
MGDB funding source(s)
National Natural Science Foundation of China (31301101, 61272339); the Anhui Provincial Natural Science Foundation (1408085QF106); the Specialized Research Fund for the Doctoral Program of Higher Education (20133401120011); Technology Foundation for Selected Overseas Chinese Scholars from Department of Human Resources and Social Security of Anhui Province (No. -243)