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Protocols

Membranome specifications

Information


Unique identifier OMICS_12533
Name Membranome
Alternative name Membrane Proteome
Restrictions to use None
Database management system MySQL
Community driven No
Data access File download, Browse
User data submission Not allowed
Version 2.0
Maintained Yes

Taxon


  • Bacteria
    • Escherichia coli
  • Plants and Fungi
    • Arabidopsis thaliana
    • Saccharomyces cerevisiae
  • Primates
    • Homo sapiens

Maintainer


  • person_outline Andrei L. Lomize

Publications for Membrane Proteome

Membranome citations

 (46)
library_books

Comparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines

2017
PMCID: 5925393
PMID: 29719786
DOI: 10.1016/j.apsb.2017.10.002

[…] targets of choice as tumor marker proteins. The expression profiles will be useful for further elucidation of tumor-specific protein expression and molecular mechanisms of anticancer drug design. The membrane proteome for the tumor cell lines tested is now available in the for public access. […]

library_books

Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pylori

2017
PMCID: 5727368
PMID: 29055967
DOI: 10.1002/mbo3.513

[…] The Hop/Hor, Hof, and Hom families of outer membrane proteins have previously been reported to constitute a major fraction of the H. pylori outer membrane proteome (Alm et al., ). These proteins are defined by virtue of the conserved “Hp_OMP” domain (Pfam01856) that they contain at their C‐terminus. To explore the complexity of the H. pylori OM […]

library_books

Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans

2017
Sci Rep
PMCID: 5620054
PMID: 28959054
DOI: 10.1038/s41598-017-11543-z

[…] The membrane proteome of an organism was defined as all proteins that contained alpha-helical transmembrane spanning regions. As transmembrane protein prediction methods can have difficulty differentiatin […]

library_books

The EAL domain protein FcsR regulates flagella, chemotaxis and type III secretion system in Pseudomonas aeruginosa by a phosphodiesterase independent mechanism

2017
Sci Rep
PMCID: 5579053
PMID: 28860517
DOI: 10.1038/s41598-017-09926-3

[…] fractions of PAK/pJN-FcsRE60A, and fold changes were very similar to those observed for PAK/pJN-FcsR (Supplementary Table ). Figure 2 Altogether, our results indicate that FcsR expression alters the membrane proteome and leads to underrepresentation of chemotaxis and flagellar proteins by a phosphodiesterase independent mechanism. […]

library_books

Identification of membrane proteome of Paracoccidioides lutzii and its regulation by zinc

2017
PMCID: 5676091
PMID: 29134119
DOI: 10.4155/fsoa-2017-0044

[…] detected in this study. Proteins related to the glycosylation pathway, such as α-1,2-mannosyltransferase (kre5p, ktr4), mannosyltransferases (PMTs), Stt3p and calnexin [], were also identified in the membrane proteome of A. fumigatus. […]

library_books

Computational Approaches for Revealing the Structure of Membrane Transporters: Case Study on Bilitranslocase

2017
Comput Struct Biotechnol J
PMCID: 5312651
PMID: 28228927
DOI: 10.1016/j.csbj.2017.01.008

[…] nces with the methods utilizing multiple sequence alignments like TOPCONS and Phobius . The low agreement between predictions obtained using different methods shows that the global properties of the membrane proteome are still a hot matter of concern . Therefore, for a relevant differentiation between globular and membrane proteins, it is suggested to apply a consensus approach based on the analy […]

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Membranome institution(s)
Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA; St Anthony Hospital, Oklahoma City, OK, USA; Department of Computational Science and Engineering, University of Michigan, MI, USA
Membranome funding source(s)
Supported by the Division of Biological Infrastructure of the National Science Foundation (NSF) [Award #1145367].

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