mentha statistics

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Protocols

mentha specifications

Information


Unique identifier OMICS_05022
Name mentha
Interface Web user interface
Restrictions to use None
Input data Some UniProt IDs.
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Bacteria
    • Escherichia coli
  • Invertebrates
    • Caenorhabditis elegans
    • Drosophila melanogaster
  • Plants and Fungi
    • Arabidopsis thaliana
    • Saccharomyces cerevisiae
  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
    • Rattus norvegicus

Maintainer


Additional information


http://mentha.uniroma2.it/about.php

Information


Unique identifier OMICS_05022
Name mentha
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data Some UniProt IDs.
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

Taxon


  • Bacteria
    • Escherichia coli
  • Invertebrates
    • Caenorhabditis elegans
    • Drosophila melanogaster
  • Plants and Fungi
    • Arabidopsis thaliana
    • Saccharomyces cerevisiae
  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
    • Rattus norvegicus

Download


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Versioning


No version available

Maintainer


Additional information


http://mentha.uniroma2.it/about.php

Publication for mentha

library_books

Mentha: a resource for browsing integrated protein-interaction networks.

2013 Nat Methods
PMID: 23900247

mentha citations

 (33)
library_books

Functional and structural characterization of osteocytic MLO Y4 cell proteins encoded by genes differentially expressed in response to mechanical signals in vitro

2018
Sci Rep
PMCID: 5928037
PMID: 29712973
DOI: 10.1038/s41598-018-25113-4

[…] rom each amino acid,. An average per-amino acid conservation was used to quantify conservation for each proteins encoded by differentially expressed genes. We collected the mouse PPI network from the mentha resource that integrates data from five manually curated source databases. With that integrative approach, the mentha resource offers arguably the most complete currently available PPI network […]

library_books

Upregulated VEGFA and DLL4 act as potential prognostic genes for clear cell renal cell carcinoma

2018
PMCID: 5875410
PMID: 29618931
DOI: 10.2147/OTT.S150565

[…] The intersection of the PPI pairs included in Mentha (http://mentha.uniroma2.it/about.php), BioGRID (https://wiki.thebiogrid.org/), and HPRD (http://www.hprd.org/) databases was taken as background, and then the DEGs were mapped into the backgrou […]

call_split

Double agents: genes with both oncogenic and tumor suppressor functions

2018
Oncogenesis
PMCID: 5852963
PMID: 29540752
DOI: 10.1038/s41389-018-0034-x
call_split See protocol

[…] We downloaded the interactome data from mentha database (http://mentha.uniroma2.it/) and used them to perform the network analysis for POTSFs, ONCs, TSGs, and NCRGs. For each gene with PPI information, we calculated its degree k and cluster […]

library_books

Identification of potential target genes for ankylosing spondylitis treatment

2018
PMCID: 5842021
PMID: 29465556
DOI: 10.1097/MD.0000000000009760

[…] According to the PPI intersections of 4 databases, including STRING (version 10.0, http://string-db.org/),[] menthe (http://mentha.uniroma2.it/about.php), BioGRID (version 3.4, https://wiki.thebiogrid.org/),[] and HRRD (Release 9, https://wiki.thebiogrid.org/),[] PPI interactions of up- and down-regulated DEGs were extract […]

library_books

A network based meta analysis for characterizing the genetic landscape of human aging

2017
Biogerontology
PMCID: 5765210
PMID: 29270911
DOI: 10.1007/s10522-017-9741-5

[…] ein interactions or co-complex associations of the encoded proteins, complemented by different types of functional relationships. In particular, the interaction data were retrieved from the resources mentha, BioPlex, and STRING. Human release 2015.11.27 of mentha was used as an integrated interaction network that combines experimentally determined and literature-curated physical protein interactio […]

library_books

Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder Enriched Interactions

2017
Int J Mol Sci
PMCID: 5751360
PMID: 29257115
DOI: 10.3390/ijms18122761

[…] We collected a set of currently available PPIs for human proteins and used this information to annotate hub proteins and their partners/interactors. The raw data on the PPI were obtained from the mentha resource []. This resource integrates expert curated PPIs obtained from a comprehensive set of five primary databases: MINT [], IntAct [,], DIP [], MatrixDB [], and BioGRID []. We extracted all […]

Citations

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mentha institution(s)
Department of Biology, University of Rome Tor Vergata, Rome, Italy; Fondazione Santa Lucia Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy
mentha funding source(s)
Supported by the European Union Framework project 7 “Affinomics” grant and the “Oncodiet” grant from the Fondo per gli Investimenti della Ricerca di Base (FIRB) project.

mentha review

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Anonymous user #29552

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Web
Great source of protein-protein interaction data mapped to UniProt protein names.