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Protocols

MERAV specifications

Information


Unique identifier OMICS_10753
Name MERAV
Alternative name Metabolic gEne RApid Visualizer
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline David Sabatini

Publication for Metabolic gEne RApid Visualizer

MERAV citations

 (32)
call_split

Genetic variants of ALDH2 rs671 and CYP2E1 rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population

2018
PMCID: 5942392
PMID: 29765251
DOI: 10.2147/CMAR.S162105
call_split See protocol

[…] CYP2E1 genes. The Genotype-Tissue Expression (GTEx) portal (https://gtexportal.org/home/; accessed July 1, 2017) was used to search for ADLH2 and CYP2E1 expression levels in different tissues and the MERAV website (http://merav.wi.mit.edu/; accessed July 1, 2017) was assessed to retrieve ADLH2 and CYP2E1 expression levels in normal and primary tumor tissues. The GeneMANIA prediction server of biol […]

library_books

Distinct prognostic value of mRNA expression of guanylate binding protein genes in skin cutaneous melanoma

2018
PMCID: 5920493
PMID: 29725478
DOI: 10.3892/ol.2018.8306

[…] 17). The patients were sorted into a percentile of 50:50 by the expression of every GBP sub-member, and then SKCM patients' survival data information was obtained.The Metabolic gEne RApid Visualizer (MERAV: http://merav.wi.mit.edu/SearchByGenes.html, accessed March 1, 2017) () was used to make a boxplot of GBP sub-members' expression levels in normal tissue and primary tumors of skin cancer. After […]

library_books

Prognostic and predictive value of HURP in non small cell lung cancer

2018
PMCID: 5868404
PMID: 29484418
DOI: 10.3892/or.2018.6280

[…] Kaplan-Meier method. Survival differences were further validated by KM-plotter (http://kmplot.com/analysis/index.php?p=background) (). The expression level of HURP in NSCLC cell lines was detected in Metabolic gEne RApid Visualizer (MERAV, http://merav.wi.mit.edu/SearchByGenes.html) and further validated by RT-qPCR and western blot analysis. Differences between the gene expression levels within di […]

library_books

The prognostic value of CYP2C subfamily genes in hepatocellular carcinoma

2018
PMCID: 5911570
PMID: 29479826
DOI: 10.1002/cam4.1299

[…] First, the Metabolic gEne RApid Visualizer database (http://merav.wi.mit.edu/) was accessed on September 10, 2017 to determine whether any of the four members of the CYP2C subfamily are differentially expressed between normal liver tissues and primary liver tu […]

library_books

Recently Evolved Tumor Suppressor Transcript TP73 AS1 Functions as Sponge of Human Specific miR 941

2018
Mol Biol Evol
PMCID: 5913670
PMID: 29474580
DOI: 10.1093/molbev/msy022

[…] 16579. For TP73-AS1, its expression abundance in normal and cancer cell lines was estimated using RNA-seq data from GTEx, HPA, Expression Atlas, and E-MTAB-2706 and using microarray data queried from MERAV database (http://merav.wi.mit.edu/). The mRNA and miRNA expression profiles in normal melanocytes (HEMa-LP) and melanoma (A375), shown in , were analyzed using microarray data that downloaded fr […]

library_books

Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA

2018
PMCID: 5833686
PMID: 29396474
DOI: 10.1038/s41419-017-0224-z

[…] To investigate the correlation between EZH2 and MYC, we used online Metabolic gEne RApid Visualizer (MERAV) database. MERAV is designed to analyze normalized human gene expression across 4454 arrays. Our study includes 196 different established and patient derived bre […]

Citations

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MERAV institution(s)
Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA, USA
MERAV funding source(s)
National Institutes of Health [CA103866, AI47389]; Life Science Research Foundation and Ludwig Postdoctoral Fellowship; Howard Hughes Medical Institute

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