Allows for visualization and analysis of samples in a 2D-map that emphasizes similarities between similar samples. MEREDITH is an omic integration method which is a hybrid of an early stage (concatenation-based) and intermediate stage (transformation-based) integration approach. This resource quantifies the contribution of each molecular data-type across the genome-wide dataset. It also detects known global pan-cancer clusters as well as within-tissue-of-origin clusters.
Delft Bioinformatics Lab (DBL), Delft University of Technology, Delft, the Netherlands; Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands; Precision and decentralized Diagnostics, Philips Research, Eindhoven, the Netherlands
MEREDITH funding source(s)
Supported by the Dutch public-private research community (COMMIT, project: P23).