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MergeMaid | R tools for merging and cross-study validation of gene expression data

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A package and associated object definitions to merge and visualize multiple gene expression datasets. MergeMaid uses arbitrary character IDs and generates objects that can efficiently support a variety of joint analyses. Visualization tools support exploration and cross-study validation of the data, without requiring normalization across platforms. Tools include ``integrative correlation'' plots that is, scatterplots of all pairwise correlations in one study against the corresponding pairwise correlations of another, both for individual genes and all genes combined. Gene-specific plots can be used to identify genes whose changes are reliably measured across studies. Visualizations also include scatterplots of gene-specific statistics quantifying relationships between expression and phenotypes of interest, using linear, logistic and Cox regression.

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MergeMaid forum

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MergeMaid classification

MergeMaid specifications

Unique identifier:
OMICS_02124
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Maintained:
Yes

MergeMaid distribution

versioning

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No versioning.

MergeMaid support

Documentation

Credits

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Publications

Institution(s)

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, USA

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