MET-COFEA statistics

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Citations per year

Number of citations per year for the bioinformatics software tool MET-COFEA

Tool usage distribution map

This map represents all the scientific publications referring to MET-COFEA per scientific context
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Associated diseases


Popular tool citations

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MET-COFEA specifications


Unique identifier OMICS_06729
Alternative name METabolite COmpound Feature Extraction and Annotation
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Windows
Parallelization MPI
Computer skills Medium
Stability Stable
Maintained Yes


No version available


  • person_outline Wenchao Zhang

Publication for METabolite COmpound Feature Extraction and Annotation

MET-COFEA citations


Rhizobium Impacts on Seed Productivity, Quality, and Protection of Pisum sativum upon Disease Stress Caused by Didymella pinodes: Phenotypic, Proteomic, and Metabolomic Traits

Front Plant Sci
PMCID: 5699443
PMID: 29204150
DOI: 10.3389/fpls.2017.01961

[…] In a second strategy, MS RAW files were converted to CDF format by Xcalibur (version 2.3.26) (Thermo Fisher Scientific Inc.). The CDF files were loaded into the LC-MS data analysis tool MET-COFEA (metabolite compound-associated feature extraction and annotation algorithms) () with the following parameter configurations: intensity cut-off threshold 10,000, ppm threshold 200 for mass t […]


Metabolomics for Plant Improvement: Status and Prospects

Front Plant Sci
PMCID: 5545584
PMID: 28824660
DOI: 10.3389/fpls.2017.01302

[…] ion of biological samples like volatile compounds formed during bacterial growth ().Exhaustive data set generated from above high throughput tools are processed through data processing platforms like MET-COFEA, Met-Align, ChromaTOF, MET-XAlign, etc., (; ; ; , ; ; ; ). This basically includes baseline correction, alignment, separation of co-eluting peaks (deconvolution), normalization, etc. (Figure […]


From chromatogram to analyte to metabolite. How to pick horses for courses from the massive web resources for mass spectral plant metabolomics

PMCID: 5499862
PMID: 28520864
DOI: 10.1093/gigascience/gix037

[…] abolite Profiles; MAVEN: Metabolomic Analysis and Visualization Engine; MeKO: Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis; MetCCS: Metabolite Collision Cross-Section Predictor; MET-COFEA: Metabolite Compound Feature Extraction and Annotation; MET-COFEI: Metabolite Compound Feature Extraction and Identification; MET-IDEA: Metabolomics Ion-Based Data Extraction Algorithm; METL […]

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MET-COFEA institution(s)
Plant Biology Division, The Samuel Roberts Noble Foundation, Ardmore, Oklahoma, USA

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