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MetABEL specifications

Information


Unique identifier OMICS_00237
Name MetABEL
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 0.2-0
Stability Stable
Maintained No

Versioning


No version available

Documentation


Maintainer


This tool is not available anymore.

Publication for MetABEL

MetABEL citations

 (17)
library_books

The GenABEL Project for statistical genomics

2016
F1000Res
PMCID: 4916982
PMID: 27347381
DOI: 10.5256/f1000research.9397.r14057

[…] is an R package for running genome-wide association analyses using mixed models in quantitative traits.GWAS usually involves meta-analysis of the regression results of various cohorts. The R package MetABEL provides simple meta-analysis functions including generation of forest plots.The R package VariABEL can be used to look for variance heterogeneity in genetic studies. Such heterogeneity is an […]

library_books

Laser Feedback Interferometry as a Tool for Analysis of Granular Materials at Terahertz Frequencies: Towards Imaging and Identification of Plastic Explosives

2016
PMCID: 4813927
PMID: 27005629
DOI: 10.3390/s16030352

[…] r to minimize tilt and position effects [] creating a flat 3 mm diameter surface for scanning. All of the three samples were granular systems: SX2 [1,3,5-trinitroperhydro-1,3,5-triazine (RDX) based], Metabel [1,3-dinitrato-2,2-bis(nitratomethyl)propane (PETN) based], and Semtex-H (RDX and PETN based).Material from each of the plastic explosives from the same batch was separately made into pellets […]

library_books

Meta‐analysis of genome‐wide association from genomic prediction models

2015
Anim Genet
PMCID: 4738412
PMID: 26607299
DOI: 10.1111/age.12378

[…] cy to the widespread use of MA in human GWA, there are a number of programs available to perform these types of analysis that share common features (metaqtl, Veyrieras et al. ; metal, Willer et al. ; metabel, Aulchenko et al. ; gwama, Mägi & Morris ). Moreover, Bayesian approaches to MA of GWA have been proposed (Han & Eskin ). Most of these programs require the specification of population‐specifi […]

call_split

A Multi Breed Genome Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12

2015
PLoS One
PMCID: 4532498
PMID: 26261983
DOI: 10.1371/journal.pone.0134720
call_split See protocol

[…] GWA meta-analysis of the three independent datasets (breeds) was carried out using MetABEL v0.2.0 [], a part of the R statistical suite v3.0.2 []. Assuming the associated shared allelic effect being the same in each dataset, MetABEL performs a fixed effects meta-analysis, where each […]

library_books

Modulation of Genetic Associations with Serum Urate Levels by Body Mass Index in Humans

2015
PLoS One
PMCID: 4374966
PMID: 25811787
DOI: 10.1371/journal.pone.0119752

[…] udies to implement association testing are reported in .The results from all individual GWA scans were combined into a fixed-effects meta-analysis using inverse variance weighting, implemented in the MetABEL R package []. From individual-study analysis, SNPs with minor allele frequency less than 1% or low imputation quality (assessed by the metrics r2hat (MACH) <0.3 or. info (IMPUTE) <0.4) were ex […]

library_books

A Genome Wide Meta Analysis Study for Identification of Common Variation Associated with Breast Cancer Prognosis

2014
PLoS One
PMCID: 4272267
PMID: 25526632
DOI: 10.1371/journal.pone.0101488

[…] timetres) as covariates.Cochran’s Q-statistic and the resultant p-value was used to detect heterogeneity in association estimates between POSH and HEBCS. Genome wide meta-analysis was performed using MetABEL . […]

Citations

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MetABEL institution(s)
Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, Rotterdam, The Netherlands; Statistical Genetics Group, Max-Planck-Institute of Psychiatry, Munich, Germany
MetABEL funding source(s)
Supported by the Netherlands Organization for Scientific Research (NWO-RFBR 047.016.009), the Centre for Medical Systems Biology (CMSB), and the Russian Foundation for Basic Research (RFBR).

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