MetaboLyzer statistics

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MetaboLyzer specifications

Information


Unique identifier OMICS_02649
Name MetaboLyzer
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

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Publication for MetaboLyzer

MetaboLyzer in pipeline

2018
PMCID: 5940876
PMID: 29740146
DOI: 10.1038/s41598-018-25588-1

[…] indices and derivatization. data was processed, aligned, and analyzed using chromatof v. 4.51.6.0 with the statistical compare function (leco, st. joseph, mi), metaboanalyst, and in house software metabolyzer as previously described., cells were seeded at a density of 1,000 cells per well in 3, 96-well plastic tissue culture dishes per cell line on day 0. on day 1, one plate was stained […]


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MetaboLyzer in publications

 (7)
PMCID: 5710696
PMID: 28902579
DOI: 10.1080/19382014.2017.1356558

[…] a data matrix that consisted of the retention time, m/z value, and the normalized peak area. statistical analysis and putative ion identification on the post-processed data were conducted utilizing metabolyzer. lipid ions were validated with the fragmentation provided in mse results. metabolic pathway information from kegg as well as biocyc was further utilized for creating pathway hit […]

PMCID: 5575047
PMID: 28852188
DOI: 10.1038/s41598-017-10299-w

[…] showed significant bone marrow aplasia, providing evidence that hematopoietic syndrome was induced. the normalized dataset for electrospray ionization (esi+ and esi−) modes were processed through metabolyzer and a standard singular value decomposition based principal component analysis (pca) was performed. examples of volcano plots, pca plots, and heatmaps indicate differences […]

PMCID: 5499862
PMID: 28520864
DOI: 10.1093/gigascience/gix037

[…] functions, but also a variety of software tools exist that combine procedures relevant to metabolomics in a single pipeline, thus facilitating the workflow, such as deviumweb [], biostatflow [], metabolyzer [], metap-server [], fusion [], pathomx [], msprep [], mixomics [], and covariance inverse (covain) []., other interesting and somehow more specialized tools include repexplore [], […]

PMCID: 4881599
PMID: 27213362
DOI: 10.3390/ijms17050782

[…] 13.6 ± 0.96 μg/ml, for days 7–9 at cumulative skeleton dose of 2.0 gy was 8.4 ± 0.46 μg/ml, and for days 25–30 at 5.0 gy was 7.5 ± 0.90 μg/ml., our initial statistical analysis was carried out in metabolyzer (washington, dc, usa) as described previously []. briefly, metabolyzer was used to select ions (m/z) that were present in at least 70% of the samples in all study groups with nonzero […]

PMCID: 4286155
PMID: 25333951
DOI: 10.1021/pr500913n

[…] but also gain structural information on these chemical species. furthermore, we utilized a comprehensive statistical analysis workflow we have specifically developed for metabolomics, called metabolyzer, to determine 137cs-specific perturbations in metabolites/lipids and their respective pathways. the statistically significant metabolites and lipids were then compared with known […]


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MetaboLyzer institution(s)
Lombardi Comprehensive Cancer Center, Biochemistry and Molecular and Cellular Biology Georgetown University Medical Center, NW, USA

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