Allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). MetaboSignal is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. This approach is ideally suited to identify candidate genes in metabotype-Quantitative-Trait Locus (QTL) or to identify biological pathways affected in transgenic models. This approach is ideally suited to identify candidate genes in metabotype-QTL studies (e.g. trans-acting associations), or to identify biological pathways affected in transgenic models.