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MetaCore specifications


Unique identifier OMICS_02716
Name MetaCore
Interface Web user interface
Restrictions to use License purchase required
License Commercial
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Jaimie Brown

MetaCore citations


Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjects

BMC Genomics
PMCID: 5941680
PMID: 29739336
DOI: 10.1186/s12864-018-4670-5

[…] MetaCore pathway analysis on the 255 filtered differentially expressed target genes from the previous analysis revealed 112 perturbed pathways (corrected P < 0.01; Table , Additional file : Table S5). […]


Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat

PMCID: 5952427
PMID: 29766046
DOI: 10.1523/ENEURO.0436-17.2018
call_split See protocol

[…] fferential expression determined using DESeq2. Adjusted p < 0.05 and log2 fold change >0.5 or <-0.5 were used as the cutoff for differential expression. Significantly regulated genes were uploaded to MetaCore for downstream analysis to determine Gene Ontology (GO) processes and molecular functions that were significantly altered in Nav-Tsc2 mice. […]


Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue

PLoS One
PMCID: 5905995
PMID: 29668675
DOI: 10.1371/journal.pone.0193792

[…] acetyl-L-aspartic acid 1) had a fold change greater than 2, when comparing Cluster 1 to Cluster 2 (). Enrichment of endogenous pathways were mapped using all 11 library-matched metabolites in GeneGo (MetaCore). pictorially represents the most significantly enriched pathways, based on the Cluster 1/Cluster 2 fold-change differences and p-value thresholds listed in . […]


Development and Characterization of an Endotoxemia Model in Zebra Fish

Front Immunol
PMCID: 5884884
PMID: 29651289
DOI: 10.3389/fimmu.2018.00607
call_split See protocol

[…] FQ intensities, and only proteins with a p-value of <0.05 and a fold change greater than 1.5 or less than −1.5 were used for the heat map and pathway analyses. The pathway analysis was conducted with MetaCore™ version 6.30 build 68,780, and the selected genes were mapped to the Homo sapiens pathways. Proteomic data were deposited to Mass Spectrometry Interactive Virtual Environment (MassIVE) at UC […]


Chemotherapy and terminal skeletal muscle differentiation in WT1‐mutant Wilms tumors

PMCID: 5911586
PMID: 29542868
DOI: 10.1002/cam4.1379
call_split See protocol

[…] “pheatmap” available from CRAN (cran.r‐ Gene expression data can be found at GEO: GSE63616 and GSE102723. To identify biological processes associated with gene expression profiles, the MetaCore software suite ( was used. The normalized microarray data from up‐ and down‐regulated data sets were uploaded into MetaCore. We selected genes with a minim […]


Targeting Hodgkin and Reed–Sternberg Cells with an Inhibitor of Heat Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance

Int J Mol Sci
PMCID: 5877697
PMID: 29534015
DOI: 10.3390/ijms19030836

[…] .5) was considered to be indicative of significantly altered levels of expression. After filtering, protein data and associated expression profiles were used as input for the curated pathway database Metacore™ software (GeneGO Inc., Saint Joseph, MI, USA). […]


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