Metadisorder

[…] mains. Four α-helices were located in the N-terminal and the remaining 6 α-helices at the C-terminal (). The majority of the non-helical regions seem to contain random coil motifs. Analysis using the MetaDisorder series implemented in the GeneSilico Metadisorder service has identified 3 intrinsically unstructured or disordered regions that span codons 27–36, 46–102 and 121–241, referred here as do […]

[…] et-based prediction sites to identify likely structural features of the endogenous DUX4-FL protein. Sites that we consulted include RaptorX at http://raptorx.uchicago.edu/StructurePrediction/ () (A); MetaDisorder at http://genesilico.pl/metadisorder/ (); Phyre2 at http://www.sbg.bio.ic.ac.uk/~phyre2 (); Robetta at http://robetta.bakerlab.org (); and the Eukaryotic Linear Motif Resource at http://e […]

[…] we subjected a single CFBP sequence to disorder prediction by multiple programs, and the PrDOS results agreed with essentially all of them, including several meta-predictors (data not shown), such as MetaDisorder, which compares nearly two dozen different methods [], and PONDR-FIT, which combines five []. For routine analysis, the PrDOS results were downloaded as CSV (comma-separated values) files […]

[…] nce accession numbers are KX660743 for HvASR1 and KX660744 for TtASR1. Disordered regions within HvASR1 and TtASR1 were identified using the MeDor (http://www.vazymolo.org/MeDor/), and the Genesilico MetaDisorder (http://iimcb.genesilico.pl/metadisorder/metadisorder.html) metaservers for the prediction of disorder. These metaservers collect disorder and secondary structure predictions from servers […]

[…] Local prediction of Intrinsically Unstructured Protein Regions (protein disorder) from amino acid sequences (). Method: MetaDisorderMD2. Server at: http://iimcb.genesilico.pl/metadisorder/metadisorder.html. […]

[…] e/). Conservation scores for each myotilin residue in the multiple sequence alignment (MSA) were calculated using the Scorecons server. Disorder tendency prediction was performed using the GeneSilico MetaDisorder server.ConSurf-DB was used for presentation of evolutionary conservation profiles of myotilin Ig domains. Pre-calculated MSA for Ig1 consisted of 301 homologues and 152 homologues for Ig2 […]