Metadisorder statistics

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Metadisorder specifications


Unique identifier OMICS_03634
Name Metadisorder
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Lukasz Kozlowski <>

Publication for Metadisorder

Metadisorder in pipelines

PMCID: 4342033
PMID: 25568342
DOI: 10.1091/mbc.E14-08-1290

[…] cd30 was analyzed by web-hosted bioinformatics tools for similarities to other proteins: blast (); t-coffee (); secondary structure prediction (jpred; ); prediction of disordered regions (genesilico metadisorder; ); and fold recognition (i-tasser; ). the structure prediction method i-tasser () predicts that cd30v could fold into a compact α/β domain, but the confidence of the prediction […]

PMCID: 4481407
PMID: 26110638
DOI: 10.1371/journal.pgen.1005260

[…] catalyze ubiquitin transfer as it lacks the cysteine that forms a transient thioester bond with the c-terminus of ubiquitin (ub)., prediction of potentially disordered regions using the genesilico metadisorder server ( revealed that at the c-terminus of peo there is a stretch of ~ 70 aa (from residue 177 to 244, according swissprot numbering) […]

PMCID: 4481533
PMID: 26110528
DOI: 10.1371/journal.pgen.1005167

[…] aktip exhibits an hpl tripeptide (hph in peo) instead of the hpn peptide, which is a canonical signature of the e2 superfamily. prediction of potentially disordered regions using the genesilico metadisorder server revealed that at the n and c termini of aktip there are stretches of ~ 70 aa that have a tendency to be intrinsically disordered. aktip modeling was performed using the composite […]

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Metadisorder in publications

PMCID: 5936065
PMID: 29618456
DOI: 10.1242/bio.033977

[…] prediction sites to identify likely structural features of the endogenous dux4-fl protein. sites that we consulted include raptorx at () (a); metadisorder at (); phyre2 at (); robetta at (); and the eukaryotic linear motif resource […]

PMCID: 5852385
PMID: 29552333
DOI: 10.1016/j.csbj.2017.12.002

[…] subjected a single cfbp sequence to disorder prediction by multiple programs, and the prdos results agreed with essentially all of them, including several meta-predictors (data not shown), such as metadisorder, which compares nearly two dozen different methods [], and pondr-fit, which combines five []. for routine analysis, the prdos results were downloaded as csv (comma-separated values) […]

PMCID: 5686140
PMID: 29138428
DOI: 10.1038/s41598-017-15299-4

[…] presence of glycerol, zinc or 2,2,2-trifluoroethanol (tfe)., the amino acid sequences of hvasr1 and ttasr1 were analyzed using the metaserver for predicting protein disorder (medor) and genesilico metadisorder metaservers (fig. ). from hydrophobic cluster analysis (hca), both proteins appear depleted in hydrophobic clusters, indicative of protein disorder (fig. ). additionally, the two […]

PMCID: 5601048
PMID: 28955362
DOI: 10.3389/fpls.2017.01572

[…] because it is an intrinsically disordered protein region (idpr) and recalcitrant to crystallization (). this idea is supported by the local disorder prediction of avp1 sequence (figure ; genesilico metadisorder tool; ) that predicts the amino-acid residues 40–63 of the m1-m2 loop are disordered. interestingly, we found other idpr or potentially flexible loops in avp1 that include […]

PMCID: 5479843
PMID: 28638118
DOI: 10.1038/s41598-017-03323-6

[…] conservation scores for each myotilin residue in the multiple sequence alignment (msa) were calculated using the scorecons server. disorder tendency prediction was performed using the genesilico metadisorder server., consurf-db was used for presentation of evolutionary conservation profiles of myotilin ig domains. pre-calculated msa for ig1 consisted of 301 homologues and 152 homologues […]

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Metadisorder institution(s)
Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, Warsaw, Poland

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