MetaDrug specifications

Information


Unique identifier OMICS_15730
Name MetaDrug
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux
Computer skills Medium
Stability No
Maintained No

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MetaDrug in publications

 (16)
PMCID: 5563918
PMID: 28835770
DOI: 10.1186/s13020-017-0145-x

[…] is extensively used for the treatment of menstrual disorders. however, its underlying pharmacological mechanisms have not been fully elucidated., a list of qxhc putative targets were predicted using metadrug. an interaction network using links between qxhc putative targets and the known therapeutic targets of menstrual disorders was constructed. qxhc candidate targets were also identified via […]

PMCID: 4949467
PMID: 27431009
DOI: 10.1038/srep29823

[…] version 9.1) were used for the collection of ppi data., putative targets of the chemical components contained in radix salviae miltiorrhizae and flos carthami tinctorii were predicted by metadrug from genego, inc. metadrug predicts the putative targets for certain chemical components using three methods: (1) based on the metabase database, which contains compound-protein […]

PMCID: 5034493
PMID: 27688997
DOI: 10.1016/j.molmet.2016.06.015

[…] processes. finally, to determine the interactions between susceptibility genes from the different functional groups, gene networks were constructed. data files were analyzed with metacore + metadrug® version 6.19 build 65960 scripts 65979., total rna was reverse transcribed with tetro cdna synthesis kit (bioline, elchrom scientific ag, cham, switzerland). real-time pcr was performed […]

PMCID: 4931368
PMID: 27351382
DOI: 10.1038/bjc.2016.146

[…] survival (pfs) with mir expression was analysed using cox regression. selected tfs were chosen by association with the panel of mirs using the transcription regulation algorithm (genego metacore+metadrug version 6.23 build 67496). bladder cancer (bc) cell lines were used to investigate the previously described role of mir-21 mediating cisplatin sensitivity., the 83 patients had a median pfs […]

PMCID: 4937870
PMID: 26685285
DOI: 10.1289/ehp.1510308

[…] research studies into underlying mechanisms by which this pop mixture could produce or exacerbate metabolic diseases., for our searches, we used proprietary systems biology software (metacore™/metadrug™) to conduct advanced search queries for the underlying interactions database, followed by directional network construction to identify common mechanisms for these pops within two or fewer […]


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