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metagen specifications


Unique identifier OMICS_00238
Name metagen
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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metagen citations


Analyses of caspase 1 regulated transcriptomes in various tissues lead to identification of novel IL 1β , IL 18 and sirtuin 1 independent pathways

PMCID: 5290602
PMID: 28153032
DOI: 10.1186/s13045-017-0406-2

[…] tribution and adjusted by Benjamini-Hochberg method []. To calculate the combined fold change for each gene, we meta-analyzed the fold change across studies by inverse variance weighting method using metagen function from “meta” package [].Venn analysis was performed in R statistical environment using the package “Venn Diagram” to analyze Casp1-regulated gene expression among different tissues (Ad […]


The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study

Sci Rep
PMCID: 4973233
PMID: 27487993
DOI: 10.1038/srep31121

[…] o account for population stratification. Pooled estimates of the association between BMI genetic score and the tested BMI and smoking phenotypes were obtained by fixed-effects meta-analysis using the metagen R package, and I2 statistic to quantify the proportion of the total variation due to heterogeneity were calculated. Additionally, power calculations for the MR analysis were performed acording […]


The Common Variant rs4444235 near BMP4 Confers Genetic Susceptibility of Colorectal Cancer: An Updated Meta Analysis Based on a Comprehensive Statistical Strategy

PLoS One
PMCID: 4059743
PMID: 24932582
DOI: 10.1371/journal.pone.0100133

[…] 34 controls, and performed an updated meta-analysis, using a comprehensive statistical strategy. The methodology of logistic regression was applied to estimate the most plausible genetic model in the metagen system . The generalized odds ratio, based on model-free approach, was utilized to provide a global test of genetic association . Stratified analyses were further performed to explore potentia […]

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metagen institution(s)
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece

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