Provides an ensemble-based web server for more accurate prediction of MHC-binding peptides. MetaMHC contains not only some popular base predictors, but also four types of ensemble strategies to improve the prediction accuracy significantly. It includes two components, MetaMHCI and MetaMHCII for the prediction of MHC Class I binding peptides and MHC Class II binding peptides, respectively. It can be useful in the literature for peptide-based vaccine design.
School of Computer Science and Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, China; Department of Immunology, Kochi Medical School, Kochi, Japan; Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Japan; Institute for Bioinformatics Research and Development (BIRD), Japan Science and Technology Agency (JST), Japan