Online

Provides complete insight in the quality of each sample in a large-scale EWAS and gives the user full control on the selection of bad-quality samples that should be excluded from downstream analyses. MethylAid was specifically designed for quality control of large set of DNA methylation data. The web application produces multiple interactive diagnostic plots on the basis of the quality control probes present on the 450k array that facilitate the detection of bad-quality samples irrespective of sample size.

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MethylAid versioning

No versioning.

MethylAid classification

MethylAid specifications

Software type:
Package
Restrictions to use:
None
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Version:
1.8.0
Requirements:
R
Interface:
Command line interface
Biological technology:
Illumina
Programming languages:
R
Computer skills:
Advanced
Stability:
Stable

MethylAid support

Documentation

Credits

Publications

  • (van Iterson et al., 2014) MethylAid: Visual and interactive quality control of large Illumina 450k data sets. Bioinformatics.
    PMID: 25147358

Institution(s)

Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands

Funding source(s)

This work was funded by the Biobank-based Integrative Omics Study (BIOS) Consortium funded by BBMRI-NL, a Research Infrastructure financed by the Netherlands Organization for Scientific Research (NWO 184.021.007) and partially supported by the European Union’s Seventh Framework Program (FP7/2007-2011) under grant agreement No. 259679 (IDEAL).

Link to literature

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