methylSpectrum statistics

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Citations per year

Number of citations per year for the bioinformatics software tool methylSpectrum

Tool usage distribution map

This map represents all the scientific publications referring to methylSpectrum per scientific context
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Associated diseases


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methylSpectrum specifications


Unique identifier OMICS_13681
Name methylSpectrum
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Stability No
Maintained No




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Publication for methylSpectrum

methylSpectrum citation


Association of DNA methylation with age, gender, and smoking in an Arab population

Clin Epigenetics
PMCID: 4320840
PMID: 25663950
DOI: 10.1186/s13148-014-0040-6

[…] on flow cytometry. This requires large volumes of fresh blood and labor-intensive antibody tagging. Given that the DNA methylation signature is highly correlated with the leukocyte distribution, the methylSpectrum method [] performs a deconvolution algorithm similar to quadratic programming and regression calibration to investigate association with a disease. Using external validation data, the m […]

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methylSpectrum institution(s)
College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA; Section of Biostatistics and Epidemiology, Dartmouth Medical School, Hanover, NH, USA; Department of Epidemiology, University of Minnesota, Minneapolis, MN, USA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Epidemiology, Brown University, Providence, RI, USA
methylSpectrum funding source(s)
This work was supported by the National Institute of Health (grants n°CA100679, CA126939, CA121147 and CA078609).

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