methylSpectrum statistics

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Citations per year

Number of citations per year for the bioinformatics software tool methylSpectrum
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Tool usage distribution map

This map represents all the scientific publications referring to methylSpectrum per scientific context
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Associated diseases

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methylSpectrum specifications

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Unique identifier OMICS_13681
Name methylSpectrum
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Stability No
Maintained No

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Publication for methylSpectrum

methylSpectrum citation

library_books

Association of DNA methylation with age, gender, and smoking in an Arab population

2015
Clin Epigenetics
PMCID: 4320840
PMID: 25663950
DOI: 10.1186/s13148-014-0040-6

[…] on flow cytometry. This requires large volumes of fresh blood and labor-intensive antibody tagging. Given that the DNA methylation signature is highly correlated with the leukocyte distribution, the methylSpectrum method [] performs a deconvolution algorithm similar to quadratic programming and regression calibration to investigate association with a disease. Using external validation data, the m […]


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methylSpectrum institution(s)
College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA; Section of Biostatistics and Epidemiology, Dartmouth Medical School, Hanover, NH, USA; Department of Epidemiology, University of Minnesota, Minneapolis, MN, USA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA; Department of Epidemiology, Brown University, Providence, RI, USA
methylSpectrum funding source(s)
This work was supported by the National Institute of Health (grants n°CA100679, CA126939, CA121147 and CA078609).

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