MeV protocols

MeV specifications

Information


Unique identifier OMICS_00781
Name MeV
Alternative names Multiple experiment Viewer, WebMeV
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Java
Computer skills Medium
Version 4.9.0
Stability Stable
Maintained Yes

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Documentation


Additional information


Standalone version: https://sourceforge.net/projects/mev-tm4/

Information


Unique identifier OMICS_00781
Name MeV
Alternative names Multiple experiment Viewer, WebMeV
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Documentation


Additional information


Standalone version: https://sourceforge.net/projects/mev-tm4/

Publication for Multiple experiment Viewer

MeV IN pipelines

 (5)
2017
PMCID: 5778818
PMID: 29435009
DOI: 10.3892/ol.2017.7691

[…] method was employed to corrects probe intensity values and the microarray data was then quantile-normalized (10) for the following comparisons. the normalized microarray data were analyzed using multiple experiment viewer (version 4.9.0, http://mev.tm4.org/#/welcome)., the human hcc cell line huh7 was purchased from the cell bank of type culture collection of chinese academy of sciences […]

2015
PMCID: 4600100
PMID: 26350964
DOI: 10.1128/mBio.00649-15

[…] within and between arrays using the r package limma (64) in a pipeline adapted from reference 62. resultant normalized gene expression data were subjected to student’s t test using the tm4 multiple experiment viewer (65). a cutoff of p < 0.05 between biological replicates of parent strain versus histone mutant was used to designate those genes that showed significant changes in gene […]

2013
PMCID: 3631235
PMID: 23620734
DOI: 10.1371/journal.pone.0061240

[…] in [35]. changes in the tr for rp genes were evaluated by k-means clustering using the euclidean distance of the normalized averaged value. for the cluster analysis of the results, we used the mev multiple experiment viewer (http://www.tm4.org/mev/)., total cellular rna was treated for 15 minutes at 25°c with dnase i rnase-free (roche) according to the manufacture’s protocol and prior to use […]

2013
PMCID: 3855414
PMID: 24340001
DOI: 10.1371/journal.pone.0082164

[…] the values for each lysate were normalized to the mfi-b values of the respective vehicle-treated control spots providing a fold change in phosphorylation state. these data were imported into tigr multiple experiment viewer software (tmev) [20] to create heat map representations and to perform hierarchical clustering, and significance analysis as described. time-course (two class unpaired) […]

2012
PMCID: 3425586
PMID: 22937035
DOI: 10.1371/journal.pone.0043339

[…] the microarray data have been deposited in the geo database (accession number gse38330) and described in accordance with miame guidelines. unsupervised hierarchical clustering was performed using multiple experiment viewer software (mev; http://www.tm4.org/mev/). the gene signatures identified by paugh et al. [11] for the subtype classification of pediatric high-grade astrocytomas […]

MeV institution(s)
Center for Cancer Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA
MeV funding source(s)
Supported by a grant from the US National Cancer Institute, through its Informatics Technology for Cancer Research program (5U01CA151118).

MeV review

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Martin Abba

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Desktop
MeV is a java-based desktop application with extensive capability for array and RNAseq clustering, machine learning methods (SVM), statistical analysis (t-test, ANOVA, SAM, Rank Product, edgeR, Degseq, etc.), data mining and visualization tools in an easy-to-learn graphical user interface.