MEXPRESS statistics

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Citations per year

Number of citations per year for the bioinformatics software tool MEXPRESS
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Tool usage distribution map

This map represents all the scientific publications referring to MEXPRESS per scientific context
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Associated diseases

This word cloud represents MEXPRESS usage per disease context
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Protocols

MEXPRESS specifications

Information


Unique identifier OMICS_16286
Name MEXPRESS
Interface Web user interface
Restrictions to use None
Input data A gene symbol or Ensembl id, a cancer type.
Output data The corresponding expression, DNA methylation and clinical data, as well as the relationship between these data sets.
Programming languages Javascript, PHP, R, Shell (Bash)
Computer skills Basic
Stability Stable
Maintained Yes

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Documentation


Maintainer


  • person_outline Alexander Koch

Information


Unique identifier OMICS_16286
Name MEXPRESS
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Input data A gene symbol or Ensembl id, a cancer type.
Output data The corresponding expression, DNA methylation and clinical data, as well as the relationship between these data sets.
Operating system Unix/Linux
Programming languages Javascript, PHP, R, Shell (Bash)
Database management system MySQL
License MIT License
Computer skills Medium
Stability Stable
Maintained Yes

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Versioning


No version available

Documentation


Maintainer


  • person_outline Alexander Koch

Publications for MEXPRESS

library_books

MEXPRESS: visualizing expression, DNA methylation and clinical TCGA data.

2015 BMC Genomics
PMCID: 4549898
PMID: 26306699
DOI: 10.1186/s12864-015-1847-z

MEXPRESS citations

 (5)
library_books

Associations of two pore domain potassium channels and triple negative breast cancer subtype in The Cancer Genome Atlas: systematic evaluation of gene expression and methylation

2017
BMC Res Notes
PMCID: 5596847
PMID: 28899398
DOI: 10.1186/s13104-017-2777-4

[…] Comparative analyses with the Agilent-array supports RSEM findings for KCNK5/KCNK6/KCNK12/KCNK15.Regarding specificity for association of K2p-expression with tumor vs. normal sample-type, we used the MEXPRESS web tool for visualizing expression, DNA methylation and clinical TCGA data [], and found that KCNK9 (p = 2.58 × 10−9) and KCNK12 (p = 4.63 × 10−10) overexpression appeared to be associated w […]

library_books

Epigenetic regulation of gene expression in cancer: techniques, resources and analysis

2017
Brief Funct Genomics
PMCID: 5860551
PMID: 28968850
DOI: 10.1093/bfgp/elx018

[…] te data from publicly available repositories. Notable genome browsers include the UCSC Genome Browser [, ], the Ensembl Genome Browser [], the WashU EpiGenome Browser [, ], the NCBI Map Viewer [] and MEXPRESS []. Each browser has a unique interface, set of features and capacity for data integration from external data sources. Here, we cover four browsers tailored to epigenetics data: the UCSC Geno […]

call_split

Establishment of a Strong Link Between Smoking and Cancer Pathogenesis through DNA Methylation Analysis

2017
Sci Rep
PMCID: 5431893
PMID: 28500316
DOI: 10.1038/s41598-017-01856-4
call_split See protocol

[…] idation for the identified smoking-related oncogenes. The RNA expression data are log-transformed before being utilized for statistical analysis and data visualization. By using the web-based tool of MEXPRESS, which has two main functions of Pearson correlation and the non-parametric Wilcoxon rank-sum test, we determined whether methylation probes were correlated with the extent of expression of t […]

library_books

ABCG2 is a potential prognostic marker of overall survival in patients with clear cell renal cell carcinoma

2017
BMC Cancer
PMCID: 5368932
PMID: 28347288
DOI: 10.1186/s12885-017-3224-6

[…] rs available from TCGA database (Additional file : Fig. S1, p < 0.001).The TCGA data about ABCG2 in kidney clear cell cancer are available on the scientific website http://www.oncolnc.org, and http://mexpress.be/. There are significant differences of mRNA levels of ABCG2 between normal kidney tissue and tumor (p = <0.0001), and at various stages (p = 0.024). Comparison of mRNA levels of ABCG2 were […]

library_books

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

2016
Oncotarget
PMCID: 5041900
PMID: 27029034
DOI: 10.18632/oncotarget.8308

[…] biological relevance to the VHL methylation demonstrated in this study. There is no TCGA data (based on Infinium HumanMethylation microarrays) on ccRCC for the region picked up by our analysis, (www.mexpress.be [VHL gene symbol, KIRC dataset]). However, when looking at other tumors (profiled using the more recent HM450 version of the array, e.g. in colon adenocarcinoma dataset, COAD, HM450 data f […]


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MEXPRESS institution(s)
Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium; Laboratory of Cancer Epigenetics, Université Libre de Bruxelles, Brussels, Belgium; Department of Mathematical Modeling, Statistics and Bioinformatics, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
MEXPRESS funding source(s)
Supported by grants from the Vlaamse Liga tegen Kanker (VLK) and the Fonds de la Recherche Scientifique (FNRS).

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