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Argonne National Laboratory, Mathematics and Computer Science Division, Argonne, IL, USA; University of Chicago, Chicago, IL, USA; Purdue University, School of Electrical & Computer Engineering, West Lafayette, IN, USA; Purdue University, Department of Computer Sciences, West Lafayette, IN, USA

This work was supported in part by the NIH award U01HG006537 “OSDF: Support infrastructure for NextGen sequence storage, analysis, and management,” by the Gordon and Betty Moore Foundation with the grant “6-34881, METAZen-Going the Last Mile for Solving the Metadata Crisis),” and by the U.S. Department of Energy, Office of Science, Advanced Scientific Computing Research, under contract DE-AC02-06CH11357 as part of “Resource Aware Intelligent Network Services (RAINS).”