Provides terms for annotating all aspects of a microarray experiment from the design of the experiment and array layout, through to the preparation of the biological sample and the protocols used to hybridize the RNA and analyze the data. The MGED Ontology does not attempt to incorporate terms from existing ontologies, e.g. those that deal with anatomical parts or developmental stages terms, but provides a framework to reference terms in other ontologies and therefore facilitates the use of ontologies in microarray data annotation.
Center for Bioinformatics and Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK; MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, London, UK; Ontology Workshop, Columbia, MD, USA; NIEHS, Research Triangle Park, NC, USA; NCI Center for Bioinformatics, Chinakville, MD, USA; Department of Computer Science, Kilburn Building University of Manchester, Manchester UK; Dana-Farber Cancer Institute, Boston, MA, USA
MGED Ontology funding source(s)
This work was supported in part by NIH grant 1P41HG003619-01 and NIH-NIEHS contract 273-02-C-0027.