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Protocols

MGI specifications

Information


Unique identifier OMICS_01656
Name MGI
Alternative name Mouse Genome Informatics
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Allowed
Maintained Yes
Wikipedia https://en.wikipedia.org/wiki/Mouse_Genome_Informatics

Subtools


  • GXD
  • MGD
  • MTB

Maintainer


  • person_outline Jan T. Eppig

Publications for Mouse Genome Informatics

MGI citations

 (133)
library_books

A retinoic acid dependent stroma leukemia crosstalk promotes chronic lymphocytic leukemia progression

2018
Nat Commun
PMCID: 5934403
PMID: 29725010
DOI: 10.1038/s41467-018-04150-7

[…] values” described elsewhere. After normalization, differential gene expression was performed using the limi package in R. Annotation analysis was performed using VLAD – Visual Annotation Tool at MGI (Mouse Genome Informatics). No statistical method for sample size choice was used; however, a similar number of mice is generally used in the field for similar experiments. No animals have been exclude […]

library_books

Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice

2018
BMC Genomics
PMCID: 5923191
PMID: 29703142
DOI: 10.1186/s12864-018-4667-0

[…] ernational Mouse Phenotyping Consortium. http://www.mousephenotype.org/. Accessed 15 Jun 2017.Sanger Mouse SnpViewer. http://www.sanger.ac.uk/sanger/Mouse_SnpViewer/rel-1505. Accessed 15 Jun 2017.MGI-Mouse Genome Informatics-The international database resource for the laboratory mouse. http://www.informatics.jax.org/. Accessed 15 Jun 2017.Immunological Genome Project-ImmGen. https://www.immgen.org […]

call_split

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

2018
Nat Commun
PMCID: 5923383
PMID: 29703891
DOI: 10.1038/s41467-018-03770-3
call_split See protocol

[…] down regulated at a FDR lower than 0.1. In edgeR differential expression analysis, we selected genes up or down regulated with a p-value less than 0.05. Gene ontology analysis was performed using the mouse genome informatics visual annotation display. For the analysis of the biological term fold enrichment, a ratio between the frequency of genes in our set to frequency of genes in the whole genome […]

library_books

Integrative annotation and knowledge discovery of kinase post translational modifications and cancer associated mutations through federated protein ontologies and resources

2018
Sci Rep
PMCID: 5916945
PMID: 29695735
DOI: 10.1038/s41598-018-24457-1

[…] formation, including PTMs and disease mutations. In addition to the comprehensive protein resource, UniProt, there are resources that specialize in specific species such as neXtProt for human and the Mouse Genome Informatics (MGI) for mouse. The Protein Ontology (PRO) and iPTMnet capture specific data types on proteoforms and post-translational modifications (PTMs), respectively, across multiple s […]

library_books

A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals

2018
BMC Genomics
PMCID: 5896114
PMID: 29642853
DOI: 10.1186/s12864-018-4647-4

[…] g an NCBI BLASTP search using the default parameters). We also manually verified each genome-specific gene according to ZFIN (Zebrafish International Resource Center database, http://zfin.org/), MGI (Mouse Genome Informatics, http://www.informatics.jax.org/), Xenbase (Xenopus model organism database, http://www.xenbase.org/entry/), HGNC (HUGO Gene Nomenclature Committee, http://www.genenames.org/) […]

library_books

A genomics approach reveals insights into the importance of gene losses for mammalian adaptations

2018
Nat Commun
PMCID: 5865188
PMID: 29572503
DOI: 10.1038/s41467-018-03667-1

[…] onal annotations to single out genes that could be related to a phenotypic adaptation that evolved in these lineages. We used functional annotations from gene ontology, mouse knockout phenotypes from mouse genome informatics (MGI),, human phenotypic associations from the human phenotype ontology and OMIM, and protein domain information from Interpro. For the MGI phenotype ontology, we downloaded t […]


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MGI institution(s)
The Jackson Laboratory, Bar Harbor, ME, USA
MGI funding source(s)
Supported by National Institutes of Health/National Human Genome Research Institute [U41 HG000330, R25 HG007053, U41 HG002223].

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