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MHC2Pred specifications

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Unique identifier OMICS_06693
Name MHC2Pred
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for MHC2Pred

MHC2Pred citations

 (11)
library_books

A Brief Review of Computer Assisted Approaches to Rational Design of Peptide Vaccines

2016
PMCID: 4881492
PMID: 27153063
DOI: 10.3390/ijms17050666

[…] epitopes and was tested for high-affinity hla class ii peptide binding. it was found to compare well with several other web-accessible methods for hla class ii peptide-binding prediction, such as mhc2pred (support vector machine based method for prediction of promiscuous mhc class ii binding peptides)., oany et al. [] investigated a computational approach for the design of peptide vaccines […]

library_books

Immunoinformatics and epitope prediction in the age of genomic medicine

2015
PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] another pssm approach is netmhcii/smm-align [], which was updated to use anns in 2009 []. other hla class ii epitope predictors are propred [], rankped [], tepitope [], svrmhc [], mhc2mil [] and mhc2pred., all of these tools have some predictors for the hla-dr locus. netmhcii, rankped and mhc2mil also provide predictions for hla-dq and dp. in general, the coverage of the dq and dp loci […]

library_books

Machine Learning Methods for Predicting HLA–Peptide Binding Activity

2015
PMCID: 4603527
PMID: 26512199
DOI: 10.4137/BBI.S29466

[…] the svm creates a hyperplane in the high-dimensional space of training data to classify them into different groups. svm has been used by a few servers for hla–peptide binding prediction including mhc2pred, multipred, svmhc,, prediction of peptide immunogenicity (popi), and kernel-based inter-allele peptide binding prediction system (kiss). the quantitative derivative of svm was implemented […]

library_books

A Novel Transport Mechanism for MOMP in Chlamydophila pneumoniae and Its Putative Role in Immune Therapy

2013
PMCID: 3634821
PMID: 23637791
DOI: 10.1371/journal.pone.0061139

[…] using immuno-informatics prediction servers. each 15-mer peptide was submitted to the following servers, using default parameters: netmhc iipan , smm align , nn align , sturnolio , rankpep , mhc2pred (http://www.imtech.res.in/raghava/mhc2pred/), propred , and svmhc and analysed to derive a consensus nonamer for the binding core., in an effort to identify suitable homologs of momp […]

library_books

The evolutionary significance of certain amino acid substitutions and their consequences for HIV 1 immunogenicity toward HLA's A*0201 and B*27

2013
PMCID: 3607191
PMID: 23745018
DOI: 10.6026/97320630009315

[…] virally important immunogenic epitopes. algorithms have been developed to predict immunogenic peptides restricted to both mhc class i and ii. mhc class i and ii in silico tools include propred, mhc2pred, rankpep, svmhc, mhcpred, and mhc-bps, syfpeithi, bimas, iedb_ann, epijen, rankpep, hlapred, netctl and multipred, among others. these algorithms have been shown to be useful in identifying […]

library_books

Peptide Based Vaccine Approaches for Cancer—A Novel Approach Using a WT 1 Synthetic Long Peptide and the IRX 2 Immunomodulatory Regimen

2011
PMCID: 3763406
PMID: 24213121
DOI: 10.3390/cancers3043991

[…] and f farzin., binding scores for class i peptides using algorithm available online at www.syfpeithi.de [];, binding scores for class ii peptides (i-ab and i-ad respectively) using algorithm mhc2pred available online at www.imtech.res.in/raghava/mhc2pred [];, no score indicates that the peptide was not found in the highest four […]


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MHC2Pred institution(s)
Institute of Microbial Technology, Chandigarh, India

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