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MHCBN specifications


Unique identifier OMICS_03058
Restrictions to use None
Maintained Yes


Publication for MHCBN

MHCBN citations


Analysis of viral diversity for vaccine target discovery

BMC Med Genomics
PMCID: 5763473
PMID: 29322922
DOI: 10.1186/s12920-017-0301-2

[…] man, transgenic mice and lab mice studies that match at least nine amino acids of the predicted epitopes. Epitope databases include general ones, such as the Immune Epitope Database [], SYFPEITHI [], MHCBN [], and specialized ones, such as HCV immunology database [], HIV molecular immunology database [], and influenza database, among others. PubMed or Google search should be carried out to identif […]


sNebula, a network based algorithm to predict binding between human leukocyte antigens and peptides

Sci Rep
PMCID: 4997263
PMID: 27558848
DOI: 10.1038/srep32115

[…] The workflow of the study is shown in . Qualitative Class I HLA-peptide binding data were collected and curated from four databases: AntiJen, IEDB, MHCBN and SYFPEITHI. A bipartite network of HLA-peptide binding data was then constructed. The binding data network was used to assess the performance of sNebula using leave-one-out (LOO) cross-valida […]


Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy

Genome Biol
PMCID: 4377852
PMID: 25853550
DOI: 10.1186/s13059-015-0620-6

[…] re downloaded from the Immune Epitope Database [], Dana Farber repository [], and CIG-DB []. Automatized HTTP-mediated download and HTML processing retrieved all records from the following databases: MHCBN [], PeptideDatabase [], SYFPEITHI [], and TANTIGEN []. The entries were filtered to select for HLA class I-binding epitopes. The total number of reported peptide-MHC affinities (55,000) was five […]


Predicting MHC class I epitopes in large datasets

BMC Bioinformatics
PMCID: 2836306
PMID: 20163709
DOI: 10.1186/1471-2105-11-90

[…] ology Database [], focuses on a restricted dataset. FIMM [], is of modest size and solely focuses on cellular immunology and MHCPEP [], while still widely used, has not been updated since 1998. While MHCBN [] and AntiJen [,] contain peptide entries that are not contained in IEDB, IEDB has more entries than any other existing database in this field.While IEDB is the first epitope database of signif […]


Prediction of HLA DQ8 β cell peptidome using a computational program and its relationship to autoreactive T cells

Int Immunol
PMCID: 2686615
PMID: 19461125
DOI: 10.1093/intimm/dxp039

[…] RankPep derived a weight matrix profile using DQ8-bound peptides () from the MHCPEP database (). MHC2Pred () applied a matrix optimization technique, which is motif less on the DQ8 peptides from the MHCBN and JenPep databases (, ), and employed a support vector machine approach to distinguish the DQ8 peptide binders from the non-binders ().An effective computational program was previously develop […]


On Evaluating MHC II Binding Peptide Prediction Methods

PLoS One
PMCID: 2533399
PMID: 18813344
DOI: 10.1371/journal.pone.0003268

[…] n-binders category. The result is a dataset of weighted instances.Thus, from each MHC-II benchmark dataset, we generated five versions summarized below:Three datasets of unique peptides, MHCPEP-UPDS, MHCBN-UPDS, and IEDB-UPDS extracted from MHCPEP, MHCBN, and IEDB, respectively after eliminating short peptides consisting of fewer than 9 residues, unnatural peptides, peptides with greater than 75% […]


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MHCBN institution(s)
Bioinformatics Center, Institute of Microbial Technology, Chandigarh, India

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