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MHCPred specifications

Information


Unique identifier OMICS_17786
Name MHCPred
Interface Web user interface
Restrictions to use None
Programming languages Perl
Computer skills Basic
Version 2.0
Stability Stable
Maintained Yes

Documentation


Maintainer


  • person_outline Darren Flower <>

Publications for MHCPred

MHCPred in publications

 (25)
PMCID: 5487360
PMID: 28655927
DOI: 10.1038/s41598-017-04069-x

[…] were chemically synthesized and purified through hplc (c18 rp-hplc) by the bank peptide company (hefei, china). the antigenic epitope peptide of ompa was predicted by the online abcpred and mhcpred programs. both of the hepcidin and ompa peptides were coupled to keyhole limpet hemocyanin (klh, bank peptide company, hefei, china) at a ratio of 10 mg:10 mg (carrier/peptide), respectively. […]

PMCID: 5351307
PMID: 28357070
DOI: 10.3892/br.2016.827

[…] cytotoxic t lymphocyte restricted epitopes of platelet membrane glycoprotein iib/iiia (gp iib/iiia) antibody of human and mice were predicted using syfpeithi, rankpep, bimas, svmhc, predep, mhcpred and propred software, and the t cell epitopes of gp iib/iiia antibody were predicted. in a different study conducted by shen et al (), the secondary structure and surface characteristics […]

PMCID: 5025611
PMID: 27634541
DOI: 10.1186/s12864-016-2951-4

[…] by using netsurfp []. vaxijen v2.0 was used to check the antigenicity of the epitopes (threshold value >0.4) []. the epitopes having values more than 0.4 were considered potentially antigenic. mhcpred was used to calculate the half maximal inhibition concentration (ic50) score for drb1*0101 (a common and prevalent allele in worldwide population) [, ]. various in silico reverse vaccinology […]

PMCID: 4899534
PMID: 27335622
DOI: 10.2174/1874285801610010097

[…] sequence. these tools at iedb (www.cbs.dtu.dk/services/netctl predict the half maximal (50%) inhibitory concentration (ic50) values for peptides binding to specific mhc molecules. in addition, mhcpred (www.jenner.ac.uk/mhcpred) and syfpeithi servers (www.syfpeithi.de/bin/ mhcserver.dll/epitopeprediction.htm) to predict epitope candidates based on the processing of peptides in the cell […]

PMCID: 4603527
PMID: 26512199
DOI: 10.4137/BBI.S29466

[…] nonbinders. due to the model separation, hmms have been developed only for a very limited number of hlas., regression models have been developed for quantitative predictions of hla–peptide binding. mhcpred implemented a qsar regression to predict hla–peptide binding affinity. in this method, individual amino acid contributions at each position are calculated using partial least squares. svrmhc […]


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MHCPred institution(s)
Edward Jenner Institute for Vaccine Research, Compton, Berkshire, UK
MHCPred funding source(s)
This work was supported by GlaxoSmithKline, the Medical Research Council, the Biotechnology and Biological Sciences Research Council and the UK Department of Health.

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