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MiChip specifications


Unique identifier OMICS_02000
Name MiChip
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.34.0
Stability Stable
Biobase, R(>=2.3.0)
Maintained Yes


No version available


MiChip citations


Magnetic nanochain integrated microfluidic biochips

Nat Commun
PMCID: 5931612
PMID: 29717124
DOI: 10.1038/s41467-018-04172-1

[…] For the detection of cancer protein biomarkers, 1 μl of standard samples (0.1–100 ng ml−1) or clinical serum samples and 1 μl of detection reagents (Magchains and SERS probes) were injected into the MiChip platform. The two streams were then mixed within the mixing chamber, and followed by target recognition, separation, and Raman measurements. Similarly, bacteria of a range of concentrations (10 […]


MicroRNA mRNA regulatory networking fine tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities

BMC Genomics
PMCID: 4970254
PMID: 27485725
DOI: 10.1186/s12864-016-2850-8

[…] The expression of ssc-miR-24-3p, ssc-miR-30a-5p, ssc-miR-126 and ssc-miR-145 were random selected for validation by qRT-PCR. The correlation coefficient between qPCR and miChip data ranged from 0.543 (p = 0.0134) to 0.6833 (p = 0.0009), suggesting a good concordance between miChip and qPCR results, as shown in Fig. .Fig. 4 […]


Microenvironment drug resistance in multiple myeloma: emerging new players

PMCID: 5312413
PMID: 27474171
DOI: 10.18632/oncotarget.10849

[…] trong correlation between miRNAs expression and IGH translocation and heterozygosity. Seckinger et al. [] investigated miRNAs expression in 92 purified MM and MGUS cells and normal plasma cells using miChip-array, that analyzes 559 human miRNAs. Compared to normal plasma cells, MM cells showed 67 differentially expressed miRNAs, and MGUS cells 20. The authors found no correlation between miRNAs ex […]


Molecularly resolved label free sensing of single nucleobase mismatches by interfacial LNA probes

Nucleic Acids Res
PMCID: 4856997
PMID: 27025649
DOI: 10.1093/nar/gkw197

[…] sulted in a significant improvement in the discrimination between highly similar (90% sequence identity) mRNAs with a simultaneous increase in on-chip capture sensitivity (). Castoldi et al. reported miChip for microRNA expression profiling using the LNA capture probes, which overcomes several challenges related to monitoring miRNA expression levels (). But its requirement of 3 days' time to yield […]


Effects of the Pinggan Qianyang Recipe on MicroRNA Gene Expression in the Aortic Tissue of Spontaneously Hypertensive Rats

PMCID: 4561872
PMID: 26379738
DOI: 10.1155/2015/154691

[…] qRT-PCR is a quantitative and specific method that can be used to distinguish a single nucleotide difference between miRNAs. Thus, involution was obtained by miChip analysis for four selected miRNAs that showed either high (miR-145) or low (miR-30) signal intensities, or high (miR-20a) or low (miRNA-98) differential expression values among the three groups […]


Identification of cytokine induced modulation of microRNA expression and secretion as measured by a novel microRNA specific qPCR assay

Sci Rep
PMCID: 4480321
PMID: 26108880
DOI: 10.1038/srep11590

[…] MiRNA expression profiling was performed using the miCHIP microarray platform as described. In brief, 500 ng of FirstChoice liver or heart total RNA were labeled with a Cy3–conjugated RNA linker (Biospring, Frankfurt, Germany) and hybridized on the mi […]

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