Detects intergenic miRNA transcription start sites (TSSs). microTSS relies on deeply sequenced RNA-Seq data. It integrates RNA-Seq data by creating ‘islands’ of transcription upstream of intergenic premiRNAs. This tool scores each candidate TSS and derives the final predictions by employing a combination of three independent support vector machine (SVM) models. It eases the annotation of primiRNAs and non-coding transcripts in general.
Department of Electrical and Computer Engineering, University of Thessaly, Volos, Greece; Laboratory for Experimental Surgery and Surgical Research ‘N.S. Christeas’, Medical School of Athens, University of Athens, Athens, Greece; Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA
microTSS funding source(s)
Supported by project ‘TOM’, ‘ARISTEIA’ Action of the ‘OPERATIONAL PROGRAMME EDUCATION AND LIFELONG LEARNING’ and is co-funded by the European Social Fund (ESF) and National Resources.