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MiMI specifications


Unique identifier OMICS_02927
Name MiMI
Alternative name Michigan Molecular Interactions
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained Yes


  • person_outline H. V. Jagadish

Publication for Michigan Molecular Interactions

MiMI citations


Evaluating the associations between human circadian rhythms and dysregulated genes in liver cancer cells

PMCID: 5727601
PMID: 29250165
DOI: 10.3892/ol.2017.7109

[…] gical General Repository for interaction Datasets (BioGRID) (), Human Protein Reference Database (), ConsensusPathDB (), Database of Interacting Proteins () and the Breast Cancer Information Core and Michigan Molecular Interactions (), and identified to be involved in circadian rhythms. Only the connected component of these 71 seed networks were considered for statistical analysis using different […]


Time course microarray analysis for identifying candidate genes involved in obesity associated pathological changes in the mouse colon

PMCID: 5120484
PMID: 27895803
DOI: 10.1186/s12263-016-0547-x
call_split See protocol

[…] using Database for Annotation, Visualization and Integrated Discovery (DAVID, https://david.ncifcrf.gov/) []. Virtual interaction network-targeted genes in the selected cluster were determined using Michigan Molecular Interactions software [, ]. In this network, genes that interacted with genes in the protein interaction data consolidated from seven public databases (Biomolecular Interaction Netw […]


Identification of key regulators of pancreatic cancer progression through multidimensional systems level analysis

Genome Med
PMCID: 4853852
PMID: 27137215
DOI: 10.1186/s13073-016-0282-3

[…] network of interacting molecules from multiple omics domains using Cytoscape 2.8, an open source platform for biomolecular network visualization []. The gene interaction network was created using the Michigan Molecular Interactions (MiMI) plugin for Cytoscape []. The network was created based on molecular interactions from multiple biological interaction databases like BIND, BioGRID, CCSB at Harva […]


Comparative Proteomic Analysis of Advanced Ovarian Cancer Tissue to Identify Potential Biomarkers of Responders and Nonresponders to First Line Chemotherapy of Carboplatin and Paclitaxel

PMCID: 4795487
PMID: 26997873
DOI: 10.4137/BIC.S35775

[…] UniProt. Based on this information, the proteins were studied for their biological interaction network in apoptosis and cancer pathways using KEGG database. The Cytoscape v2.8.0 software, and plugin Michigan Molecular Interactions were used to gather and merge human gene regulatory interactome from well-known databases, including BIND, MINT, and HPRD.– From this complete network, subnetworks for […]


Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi

PLoS Negl Trop Dis
PMCID: 4714843
PMID: 26771187
DOI: 10.1371/journal.pntd.0003747

[…] . Significance for pathway level enrichment was defined as having an enrichment score False Discovery Rate (FDR) corrected p-value < 0.05. Biological network construction was conducted with the MiMI (Michigan Molecular Interactions) database (29, 30) and the GENEMANIA algorithm [,] by querying multiple biological interaction databases including BIND, DIP, HPRD, RefSeq, SwissProt, IPI [,]. Transcri […]


Identification of Differentially Expressed IGFBP5 Related Genes in Breast Cancer Tumor Tissues Using cDNA Microarray Experiments

PMCID: 4690035
PMID: 26569312
DOI: 10.3390/genes6041201

[…] We used the ExPASy bioinformatics resource portal and MiMI (Michigan molecular interactions) database for differentially expressed genes and their interactions and pathways considered with IGFBP5. Three genes, CST1 (gene id: 1469), MMP11 (gene id: 4320) and CO […]


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MiMI institution(s)
Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI, USA

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