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MimoPro specifications


Unique identifier OMICS_20586
Name MimoPro
Interface Web user interface
Restrictions to use None
Input data The X-ray crystal structure of a source antigen stored in a protein data bank (PDB), mimotopes screened from phage display experiments.
Output data Candidate epitope through the paths aligned to corresponding mimotopes.
License GNU General Public License version 3.0
Computer skills Basic
Stability No
Maintained No


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Publication for MimoPro

MimoPro citations


Fundamentals and Methods for T and B Cell Epitope Prediction

J Immunol Res
PMCID: 5763123
PMID: 29445754
DOI: 10.1155/2017/2680160

[…] ected peptides and the 3D-structure of the selected antigen. Examples of bioinformatics tools for conformational B-cell epitope prediction using mimotopes include MIMOX [], PEPITOPE [], EPISEARCH [], MIMOPRO [], and PEPMAPPER [] ().As remarked before, methods for conformational B-cell epitope prediction generally require the 3D-structure of the antigen. Exceptionally, however, Ansari and Raghava [ […]


The Relationship Between B Cell Epitope and Mimotope Sequences

Protein Pept Lett
PMCID: 5427807
PMID: 26715528
DOI: 10.2174/0929866523666151230124538

[…] ignment with the motif to get the optimal matching short peptides. Soon afterwards, some other methods and software were proposed, such as Mapitope [,], PepSurf [], Pep-3D-Search [], EpiSearch [] and MimoPro []. In 2011, we constructed a benchmark dataset for conformational B-cell epitope prediction and evaluated five mimotope-based prediction softwares []. The result showed that in no method did […]


Conformational B Cell Epitope Prediction Method Based on Antigen Preprocessing and Mimotopes Analysis

Biomed Res Int
PMCID: 4326220
PMID: 25705652
DOI: 10.1155/2015/257030

[…] he new method. The middle part is the flow of the method.As shown in , is the module of antigen processing, and is the module of mimotope-based epitope prediction which employs the core idea of our MimoPro. […]


Peptide Vaccine: Progress and Challenges

PMCID: 4494216
PMID: 26344743
DOI: 10.3390/vaccines2030515

[…] in silico tools, the selected peptide antigens can be further sequenced and aligned with antigen sequence, and if available, 3D structures can be superimposed. Some algorithms that can be of use are MimoPro, Mimox, Pepitope, MimoDB 2.0 []; (4)Prediction of linear B cell epitopes using computerized algorithms such as propensity scale, machine-learning algorithm or a combination of these two, hybri […]


Mimotope vaccination for epitope specific induction of anti VEGF antibodies

BMC Biotechnol
PMCID: 3849980
PMID: 24073737
DOI: 10.1186/1472-6750-13-77

[…] two mimotopes and VEGF might be that the epitopes that are recognized by Avastin could be a discontinuous amino acid sequence due to the folding of peptides, thus forming a conformational epitope []. MimoPro is a new graph-based mapping method for epitope prediction using affinity-selected peptides derived from phage display experiments and is freely accessible through the MimoPro server []. We us […]


Bioinformatics Resources and Tools for Conformational B Cell Epitope Prediction

PMCID: 3736542
PMID: 23970944
DOI: 10.1155/2013/943636

[…] rovides two modes of B-cell epitope prediction: (1) mimotope-based search and (2) motif-based search.The last kind of mimotope-structure alignment B-cell epitope prediction method is a hybrid method. MimoPro, which was proposed by our team in 2011, is the first attempt to integrate the idea of different methods. The method employs the idea of patch-based and graph-based searching []. The core of M […]


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MimoPro institution(s)
School of Computer Science and Information Technology, Northeast Normal University, Changchun, China; Faculty of Chemistry, Northeast Normal University, Changchun, China; School of Information and Communication Technology, Central Queensland University, North Rockhampton, QLD, Australia; National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China
MimoPro funding source(s)
Supported by the Natural Science Foundation of Jilin Province (20101503); the Natural Science Foundation of Jilin Province (20101506); the Scientific and Technical Project of Administration of Traditional Chinese Medicine of Jilin Province (No.2010pt067).

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