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miRDB specifications


Unique identifier OMICS_00403
Name miRDB
Restrictions to use None
Maintained Yes

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miRDB citations


A Five microRNA Signature for Survival Prognosis in Pancreatic Adenocarcinoma based on TCGA Data

Sci Rep
PMCID: 5955976
PMID: 29769534
DOI: 10.1038/s41598-018-22493-5
call_split See protocol

[…] The target genes of the five-miRNA (miR-203, miR-424, miR-1266, miR-1293, and miR-4772) were predicted using TargetScan, miRDB, miRTarBase, and miRanda online analysis tools. To further enhance the reliability of the bioinformatic analysis, the overlapping target genes were identified using a Venn diagram. Using the DAV […]


MicroRNA 200a/200b Modulate High Glucose Induced Endothelial Inflammation by Targeting O linked N Acetylglucosamine Transferase Expression

Front Physiol
PMCID: 5915961
PMID: 29720943
DOI: 10.3389/fphys.2018.00355

[…] llular protein O-GlcNAcylation levels (i.e., increase protein O-GlcNAcylation causing increase OGA expression and vice versa).In this study, web-based bioinformatics analysis using miRanda-mirSVR and miRDB database revealed that the members of the miR-200 functional group 1, but not of group 2, may bind to the 3′-UTR of human OGT mRNA. However, the miRanda-mirSVR database identified all five miR-2 […]


Bioinformatics based identification of potential microRNA biomarkers in frequent and non frequent exacerbators of COPD

PMCID: 5909781
PMID: 29713155
DOI: 10.2147/COPD.S163459

[…] y handling the various types of data and performing multiple testing corrections on P-values.The accuracy for the predicted targets of candidate miRNAs was improved by the following software: PicTar, miRDB and TargetScan. Validated targets were acquired from TarBase. Briefly, we took the intersection of the three series of predicted targets and validated the targets using TarBase. […]


Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma

PMCID: 5912208
PMID: 29713196
DOI: 10.2147/CMAR.S161334

[…] Targetscan (http://www.targetscan.org/, accessed November 5, 2017), miRDB (http://www.mirdb.org/, accessed November 5, 2017), and miRTarBase (http://mirtarbase.mbc.nctu.edu.tw/, accessed November 5, 2017) were used to predict miRNA target genes. The overlapping target […]


Long Non Coding RNA GAPLINC Promotes Tumor Like Biologic Behaviors of Fibroblast Like Synoviocytes as MicroRNA Sponging in Rheumatoid Arthritis Patients

Front Immunol
PMCID: 5902673
PMID: 29692777
DOI: 10.3389/fimmu.2018.00702

[…] 4, hsa-miR-1261, hsa-miR-3127-5p, hsa-miR-4649-3p, and so on. Some of them have been already reported in oncology. The related pathway and downstream genes of GAPLINC were predicted using TargetScan, miRDB and miRanda softwares, KEGG database, and GO analysis. We selected six microRNAs as superior candidates (hsa-miR-575, hsa-miR-149-3p, hsa-miR-382-5p, hsa-miR-516a-3p, hsa-miR-1184, hsa-miR-1261) […]


Inhibition of breast cancer metastasis by co transfection of miR 31/193b mimics

PMCID: 5960762
PMID: 29796229
DOI: 10.22038/IJBMS.2018.26614.6522
call_split See protocol

[…] gested sequences were ligated into pcDNA 6.2gw/ EmGFP vector. To identify potential target genes of miR-193b and miR-31, the TargetScan (http://www.targetscan.org), miRanda (http://www.microrna.org), miRDB (http://www.mirdb.org/miRDB/) and PicTar (http://pictar.mdc-berlin.de) databases were used. […]

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miRDB institution(s)
Department of Biomedical Engineering, Washington University, St Louis, MO, USA; Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO, USA

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