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MicroRNA-disease association detection software tools | RNA interference

In the recent few years, an increasing number of studies have shown that microRNAs (miRNAs) play critical roles in many fundamental and important biological processes. As one of pathogenetic factors, the molecular mechanisms underlying human complex…
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HGIMDA
Algorithm

HGIMDA Heterogeneous Graph Inference for MiRNA-Disease Association prediction

Allows users to realize miRNA-disease association prediction. HGIMDA serves to…

Allows users to realize miRNA-disease association prediction. HGIMDA serves to discover potential miRNA-disease associations thanks to integration of disease semantic similarity, miRNA functional…

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MCMDA
Algorithm

MCMDA Matrix Completion for MiRNA-Disease Association prediction

Allows users to predict the potential miRNAs related to human diseases. MCMDA…

Allows users to predict the potential miRNAs related to human diseases. MCMDA uses a matrix completion procedure by using the known miRNA-disease associations in Human miRNA Disease Database (HMDD).…

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WBSMDA
Algorithm

WBSMDA Within and Between Score for MiRNA-Disease Association prediction

Includes different types of information. WBSMDA predicts potential miRNAs…

Includes different types of information. WBSMDA predicts potential miRNAs associated with various complex diseases. It integrates miRNA functional similarity network, miRNA-disease associations,…

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RKNNMDA
Algorithm

RKNNMDA Ranking-based KNN for MiRNA-Disease Association prediction

Allows users to predict potential related miRNAs for diseases. RKNNMA is a…

Allows users to predict potential related miRNAs for diseases. RKNNMA is a computational method of Ranking-based k-nearest-neighbor (KNN) for miRNA-Disease Association prediction which obtained an…

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SDMMDA
Algorithm

SDMMDA Super-Disease and MiRNA for potential MiRNA-Disease Association prediction

Allows users to predict potential miRNA-disease associations. SDMMDA combines…

Allows users to predict potential miRNA-disease associations. SDMMDA combines known associations, disease semantic similarity, miRNA functional similarity, and Gaussian interaction profile kernel…

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DRMDA
Algorithm

DRMDA deep representations-based miRNA-disease association

Provides an efficient computational model that offers deep…

Provides an efficient computational model that offers deep representations-based miRNA–disease association prediction. DRMDA is an algorithm that calculates the score of each miRNA–disease sample…

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RLSMDA
Desktop

RLSMDA Regularized Least Squares for MiRNA-Disease Association

Predicts novel miRNAs for diseases which do not have any known related miRNAs.…

Predicts novel miRNAs for diseases which do not have any known related miRNAs. RLSMDA is able to reconstruct the missing associations for all the diseases simultaneously. It integrates…

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RWRMDA
Desktop

RWRMDA Random Walk with Restart for MiRNA–Disease Association

Infers potential miRNA–disease associations. RWRMDA implements random walk on…

Infers potential miRNA–disease associations. RWRMDA implements random walk on the miRNA functional similarity network to prioritize candidate miRNAs for disease of interest. It is composed of three…

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IRWRMDA
Algorithm

IRWRMDA Improved Random Walk with Restart for MiRNA-Disease Association prediction

Prioritizes candidate miRNA-disease pairs for further biological experiment…

Prioritizes candidate miRNA-disease pairs for further biological experiment validation. IRWRMDA is a computational model developed to infer potential associations between miRNAs and investigated…

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NARRMDA
Algorithm
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NTSMDA
Desktop

NTSMDA MiRNA-Disease Associations based on Network Topological Similarity

Predicts potential related miRNAs for diseases by using network topological…

Predicts potential related miRNAs for diseases by using network topological similarity. NTSMDA is a network-based inference algorithm on the constructed miRNA-disease association network which allows…

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NCPMDA
Algorithm

NCPMDA Network Consistency Projection for miRNA-Disease Associations

Allows users to predict potential miRNA-disease associations. NCPMDA intends to…

Allows users to predict potential miRNA-disease associations. NCPMDA intends to discover the potential associations by calculating the score of each miRNA-disease pair using the miRNA functional…

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CHNmiRD
Web

CHNmiRD

A web-based tool for inferring novel miRNA-disease associations based on a…

A web-based tool for inferring novel miRNA-disease associations based on a complex heterogeneous network (CHN) involving 402 miRNAs and 5080 diseases. CHNmiRD integrates multiple genomic and…

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GRNMF
Desktop

GRNMF Graph Regularized non-Negative Matrix Factorization

Infers the unknown miRNA-disease associations in heterogeneous omics data.…

Infers the unknown miRNA-disease associations in heterogeneous omics data. GRNMF is a graph regularized non-negative matrix factorization framework which could work for both new diseases and miRNAs.…

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DMPred
Web

DMPred Disease-related MiRNAs Prediction

Predicts disease-related miRNAs. DMPred is a method based on non-negative…

Predicts disease-related miRNAs. DMPred is a method based on non-negative matrix factorization with sparseness constraints. This resource integrates multiple kinds of information within the…

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M2DMiners
Desktop

M2DMiners

Allows users to predict the microRNA-disease associations thanks to a…

Allows users to predict the microRNA-disease associations thanks to a combinatorial prioritization algorithm. M2DMiners contains six inference methods which aim to infer the novel associations…

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ILRMR
Algorithm

ILRMR Improved Low-Rank Matrix Recovery

Allows users to predict miRNA-disease associations. ILRMR predicts several…

Allows users to predict miRNA-disease associations. ILRMR predicts several diseases at once including those without known link to miRNAs. ILRMR integrates miRNA-miRNA similarity information,…

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KBMF-MDI
Algorithm
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CPTL
Algorithm

CPTL Collective Prediction based on Transduction Learning

Allows users to prioritize miRNAs related to disease using a collective method.…

Allows users to prioritize miRNAs related to disease using a collective method. CPTL uses a transduction learning method as local prediction model which integrates homogeneous space with…

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miRPD
Web

miRPD

An approach in which miRNAs are linked to diseases via proteins, thereby…

An approach in which miRNAs are linked to diseases via proteins, thereby directly providing biological hypotheses. Specifically, we infer miRNA–disease associations by network analysis of known or…

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RBMMMDA
Web
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DISMIRA
Algorithm

DISMIRA

Predicts miRNA-disease associations including a maximum weighted matching model…

Predicts miRNA-disease associations including a maximum weighted matching model and motif-based analysis in order to prioritize disease candidates of miRNA-disease associations. DISMIRA detects the…

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PBMDA
Desktop

PBMDA Path-Based MiRNA-Disease Association

Constructs a heterogeneous graph consisting of three interlinked sub-graphs and…

Constructs a heterogeneous graph consisting of three interlinked sub-graphs and further adopted depth-first search algorithm to infer potential miRNA-disease associations. PBMDA is a prediction model…

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