Integrates microRNA and mRNA expression data with predicted microRNA target information for analyzing microRNA-associated phenotypes and biological functions by gene set enrichment analysis (GSEA). To assign biological relevance to the integrated microRNA/mRNA profiles, MMIA uses exhaustive human genome coverage (5782 gene sets), including various disease-associated genes as well as conventional canonical pathways and Gene Ontology. MMIA provides users with miRNA-mRNA expression data combined analysis tools and broad gene sets.
Medical Sciences Program, Indiana University School of Medicine, IN, USA; Bioinformatics Program, School of Informatics, Indiana University, Bloomington, IN, USA; Indiana University Simon Cancer Center, Indianapolis, IN, USA
MMIA funding source(s)
National Institutes of Health (CA085289, CA113001); Walther Cancer Foundation; Ovar’coming Together