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miRNASNP specifications

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Unique identifier OMICS_09980
Name miRNASNP
Interface Web user interface
Restrictions to use None
Computer skills Basic
Version 2.0
Stability No
Maintained No

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Publications for miRNASNP

miRNASNP citations

 (14)
library_books

Investigation of piwi interacting RNA pathway genes role in idiopathic non obstructive azoospermia

2018
Sci Rep
PMCID: 5760646
PMID: 29317647
DOI: 10.1038/s41598-017-17518-4

[…] of HIWI2 gene and due to its position it may affect mRNA stability or may alter the binding affinity of regulatory miRNAs.We used several databases including, mirBase (http://microrna.sanger.ac.uk), miRNASNP (http://www.bioguo.org/miRNASNP/index.php), MicroSNiPer http://vm24141.virt.gwdg.de/services/microsniper/index.php), TargetScan (http:// targetscan.org/vert_71/) in order to predict miRNAs th […]

call_split

Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility

2017
Oncotarget
PMCID: 5696234
PMID: 29190968
DOI: 10.18632/oncotarget.21687
call_split See protocol

[…] In order to screen out those microRNAs that may binding to 3′UTR region of CAV1 mRNA around rs1049337, we adopted 4 database for microRNA predication, including MirSNP [], miRNASNP [], PolymiRTS Database 3.0 [], SNPinfo web server [].MicroRNA mimics were purchased from GenePharma (GenePharma, China). A 602-bp fragment of CAV1 3′UTR containing rs1049337-C or rs1049337-T […]

call_split

Association of the PLCB1 gene with drug dependence

2017
Sci Rep
PMCID: 5579249
PMID: 28860459
DOI: 10.1038/s41598-017-10207-2
call_split See protocol

[…] rter system to test the possible impact of these SNPs on the regulation of gene expression mediated by miRNAs, as previously described. The prediction tools FuncPred, mirWalk, mirSNP, mrSNP, mirdSNP, miRNASNP and RNAhybrid were used to select miRNAs which binding sites in PLCB1 is potentially affected by these SNPs. We chose the best predictions for each SNP: for rs1047383, hsa-miR-124-1, hsa-miR- […]

library_books

Rs7911488 modified the efficacy of capecitabine based therapy in colon cancer through altering miR 1307 3p and TYMS expression

2017
Oncotarget
PMCID: 5650342
PMID: 29088787
DOI: 10.18632/oncotarget.19670

[…] The polymorphisms in the pre-miRNAs and their allele frequencies were obtained from the online databases of miRNASNP 2.0 (www.bioguo.org/miRNASNP2) and NCBI dbSNP (https://www.ncbi.nlm.nih.gov/projects/SNP/), respectively (). The polymorphisms with minor allele frequencies (MAF) ≥ 10% were detected by using […]

library_books

Bivariate genome wide association meta analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

2017
Nat Commun
PMCID: 5527106
PMID: 28743860
DOI: 10.1038/s41467-017-00108-3

[…] omes)HaploReg3, http://www.broadinstitute.org/mammals/haploreg/haploreg_v3.php GWAS catalogue, http://www.ebi.ac.uk/gwas/ SIFT, http://sift.jcvi.org/ PolyPhen-2, http://genetics.bwh.harvard.edu/pph2/ miRNASNP v2, http://www.bioguo.org/miRNASNP/ PolymiRTS v3, http://compbio.uthsc.edu/miRSNP/search.php miRbase http://www.mirbase.org/ TargetScan v7.1, http://www.targetscan.org/vert_71/ UCSC Genome Br […]

library_books

Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population

2017
PLoS One
PMCID: 5421813
PMID: 28481918
DOI: 10.1371/journal.pone.0177421

[…] s in miRNA binding sites of 3´UTR region of CDKN2A and CDKN2B with a MAF>10% identified using bioinformatics tools: Ensembl (http://www.ensembl.org/) (Welcome Trust Genome Campus, Cambridge, UK), and miRNASNP (http://bioinfo.life.hust.edu.cn/miRNASNP2/index.php) (College of Life Science and Technology, HUST). Of 47 SNPs identified in the 3´UTR region that disrupt or create miRNA binding sites (), […]


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miRNASNP institution(s)
Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

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