miRNet protocols

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miRNet specifications

Information


Unique identifier OMICS_11694
Name miRNet
Interface Web user interface
Restrictions to use None
Input data A list of IDs (miRNAs, genes, lncRNAs), a list of available database entries (disease names, small molecules and epigenetic modifiers) or a data table (qRT-PCR, microarray or RNA-seq) from miRNA/mRNA expression studies
Programming languages Javascript, R
Database management system SQLite
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Jianguo Xia <>

Publication for miRNet

miRNet in pipeline

2018
PMCID: 5872397
PMID: 29587824
DOI: 10.1186/s13059-018-1420-6

[…] gene list was acquired from cbioportal using a pearson correlation > 0.3 or < − 0.3. mirna targeting and network analysis was performed with mirdb (http://www.mirdb.org/mirdb/) and mirnet (http://www.mirnet.ca/) databases. relationships between gene expression and patient survival were determined by the survival p value, calculated with a r package “survival” […]


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miRNet in publications

 (7)
PMCID: 5935709
PMID: 29728663
DOI: 10.1038/s41598-018-25498-2

[…] mirnas (supplementary table ). to understand the correlation between significantly dysregulated mirnas and their target proteins, mirna-gene interaction network analysis was generated using mirnet tool. the 10 mirnas significantly dysregulated in okf6/tert1-tobacco cells showed directional relationship with 36 target proteins identified in proteomics data (fig. ). reverse transcriptase […]

PMCID: 5923293
PMID: 29703916
DOI: 10.1038/s41598-018-24424-w

[…] period of 72 hours (supplementary figure ).figure 5, identifying the target genes of the putative mirna biomarkers is important in understanding their functions. in silico pathway analysis using the mirnet web-based platform generated target genes and candidate pathways for the mirnas (supplementary figure ; supplementary tables  and ). the mirnet predicted targets are determined experimentally […]

PMCID: 5930463
PMID: 29725252
DOI: 10.7150/ijms.24061

[…] that were continuously up-regulated in adenoma progression (in normal vs. low-/high-grade adenoma) by taqman microrna assays were selected: hsa-mir-421, hsa-mir-29b-1-5p, and hsa-mir-27b-5p. using mirnet web database (www.mirnet.ca/) we acquired pathway enrichment from gene ontology . using the kegg pathway databases, we examined the pathway target enrichment (p<0.05) of selected groups […]

PMCID: 5590913
PMID: 28886082
DOI: 10.1371/journal.pone.0184209

[…] modifiers. computational prediction of target genes of mir-29b using mirwalk database (zmf.umm.uni-heidelberg.de/apps/zmf/mirwalk2/) identified dnmt1, dnmt3a, dnmt3b and mbd2 as putative targets (). mirnet database (www.mirnet.ca.) provided a mirna-target interaction network presenting various targets of dnmts []., to test the possibility that mir-29b regulates these genes, we assessed […]

PMCID: 5513884
PMID: 28744145
DOI: 10.2147/OTT.S138143

[…] were used for the target prediction of mir-144-3p, and the predicted target genes of mir-144-3p that were reported in at least four databases were selected. three databases (mirtarbase, tarbase and mirnet) were searched to obtain the validated targets of mir-144-3p.– next, we combined the two parts to identify the target genes of mir-144-3p and applied the target genes to further gene […]


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miRNet institution(s)
Institute of Parasitology, McGill University, Sainte Anne de Bellevue, Québec, Canada; Centre for Host-Parasite Interactions, McGill University, Sainte Anne de Bellevue, Québec, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada; Department of Animal Science, McGill University, Sainte Anne de Bellevue, Québec, Canada
miRNet funding source(s)
The McGill Startup Fund and the Natural Sciences and Engineering Research Council of Canada (NSERC, 243185); the Canadian Institute for Health Research (CIHR); NSERC (169998-2012)

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