Tool stats & trends
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|Interface||Web user interface|
|Restrictions to use||None|
|Input data||Results of a global mRNA expression data|
- person_outline Pascal Barbry
Publication for miRonTop
“Seed Milarity” Confers to hsa miR 210 and hsa miR 147b Similar Functional Activity
[…] is mandatory to establish a minimal set of mRNA modulated by a given miRNA and offer the opportunity to identify miRNAs with overlapping regulatory functions. Using our recently described application MiRonTop and a large set of miRNA-overexpressed microarray experiments, we noticed indeed a close relationship between two miRNAs from distinct families, hsa-miR-147b and hsa-miR-210. While these 2 s […]
Deregulated MicroRNAs in Myotonic Dystrophy Type 2
[…] /mRNAs couples displaying a statistically significant reciprocal correlation of their expression levels were included; 3) among the genes passing filters 1 and 2, predicted targets were identified by MiRonTop . After this highly selective selection, 1,093 miRNA/mRNA interactions were identified. Several mRNAs were targeted by more than one miRNA, leading to a potential reinforcement of the final d […]
Identification of microRNA precursors based on random forest with network level representation method of stem loop structure
[…] unction, the identification of miRNA targets using computational methods has developed in an increasing number. Recent improvements in this field have been reported in Li J et al , Target-align , MiRonTop , etc.Recent studies showed various ways to represent RNA structure with graphs (Figure ), such as bracketed, tree, dual graph, etc. These representations specify the connectivity between R […]
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