miRPD specifications

Information


Unique identifier OMICS_10688
Name miRPD
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Lars Juhl Jensen <>

Publication for miRPD

miRPD in publications

 (4)
PMCID: 5915491
PMID: 29691434
DOI: 10.1038/s41598-018-24532-7

[…] established a complex network by integrating mirna–target interactions, disease–gene associations and ppi. they used a random walk algorithm for prediction. mork et al. also proposed a method called mirpd. this model integrates the protein–disease association and mirna–protein interaction to further predict new mirna–disease association. with this method, disease-associated mirnas […]

PMCID: 5867860
PMID: 29498680
DOI: 10.3390/genes9030139

[…] methods do not allow identification of the underlying proteins involved in mirna-disease associations. in order to reveal the underlying proteins, mørk et al. [] developed a protein-driven method, mirpd, to infer mirna-disease associations by using mirna-protein associations and protein-disease associations. without using any known information of mirna-disease relationships, this method […]

PMCID: 5601672
PMID: 28938576
DOI: 10.18632/oncotarget.17226

[…] from primary sequences., le [] constructed a mirna function network based on common targets and applied four network-based methods to infer novel disease-related mirnas. mørk et al. [] presented mirpd to infer mirna-disease associations by coupling known and predicted mirna–protein associations with protein–disease associations. zeng et al. [, ] suggested two predictive methods on multipath […]

PMCID: 4402579
PMID: 25860109
DOI: 10.1186/1471-2105-16-S5-S5

[…] well., we then analyzed the role of the mirna eqtls in different diseases including cancer and particularly ovarian cancer. using multiple datasets (hmdd2, mircancer, phenomir, mirdsnp, mir2disease, mirpd and marchini) [-], we found that 19 of the 22 mirnas have been implicated in some type of disease. of these mirnas, 14 were associated with a form of cancer, and 12 were specifically associated […]


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miRPD institution(s)
Center for non-coding RNA in Technology and Health, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark; Department of Veterinary Clinical and Animal Sciences, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark; Department of Disease Systems Biology, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark; The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Denmark
miRPD funding source(s)
The Danish Council for Independent Research (Technology and Production Sciences), Danish Center for Scientific Computing, The Danish Council for Strategic Research (Programme Commission on Strategic Growth Technologies), The Novo Nordisk Foundation Center for Protein Research and the Danish Center for Scientific Computing

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