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miRscan specifications

Information


Unique identifier OMICS_07323
Name miRscan
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Chris Burge

Publications for miRscan

miRscan citations

 (38)
library_books

Tools for Sequence Based miRNA Target Prediction: What to Choose?

2016
Int J Mol Sci
PMCID: 5187787
PMID: 27941681
DOI: 10.3390/ijms17121987

[…] dict putative genes and their products, including the non-coding ones [,,]. A large number of genes and their ncRNAs in different species were identified [,,,]. Some miRNA prediction software such as MiRscan estimated the number of miRNA genes between two and three hundred in the human genome, although not all were experimentally validated []. The number of identified miRNA genes increased rapidly […]

library_books

MicroRNA: Biological and Computational Perspective

2016
PMCID: 5172550
PMID: 16393143
DOI: 10.1016/S1672-0229(05)03011-1

[…] arious species, including C. elegans , , , D. melanogaster , human , , , , , Arabidopsis and other plants , , , , and virus , . Two of the programs developed to predict miRNA genes are MiRseeker and MiRscan , , .Methods to find miRNA genes computationally usually utilize the following properties of known miRNA genes:1. The precursor of miRNAs can form stable extended stem-loop structures, with co […]

library_books

Well characterized sequence features of eukaryote genomes and implications for ab initio gene prediction

2016
Comput Struct Biotechnol J
PMCID: 4975701
PMID: 27536341
DOI: 10.1016/j.csbj.2016.07.002

[…] ing as candidates of miRNA genes, which could be computationally deduced on basis of the estimated free energy by tools of RNAfold and Mfold . Actually, the homology search-based approaches, such as MiRscan and miRseeker , were also designed to first scan intergenic regions of entire genome and generate full list of candidates according to the deduced hairpin sequences before homology search. Th […]

library_books

Bioinformatic tools for microRNA dissection

2015
Nucleic Acids Res
PMCID: 4705652
PMID: 26578605
DOI: 10.1093/nar/gkv1221

[…] methods predicted putative miRNAs in genome sequences by targeting secondary RNA structure, i.e. conserved hairpin structures that are characteristic of miRNA precursor sequences in related species. MiRscan () and miRseeker () are the main tools that target conserved intragenic sequences that can form hairpin structures based on RNAfold and Mfold, respectively. MiRscan then compares the identifie […]

library_books

Overview of research on Bombyx mori microRNA

2014
PMCID: 4222307
PMID: 25368077
DOI: 10.1093/jis/14.1.133

[…] sible miRNAs, and a novel small RNA were identified in B. mori. Among those identified, there were 12 pairs of miRNAs and miRNA*s ( ). In other applications of miRNA predictive bioinformatics, used miRscan and PatScan algorithms and predicted 120 iRNA genes on the 6x and 9x genome assembly of B. mori based on sequence conservation and structural similarity to known miRNAs. […]

call_split

MicroRNAs the Next Generation Therapeutic Targets in Human Diseases

2013
Theranostics
PMCID: 3881095
PMID: 24396504
DOI: 10.7150/thno.7026
call_split See protocol

[…] the gene, is a major thrust research area. Due to many imperative functions of these tiny gene regulators, like patterning of nervous system, miRNA genes are planned to be identified, which develops miRscan and conserved in more than one genome. The conserved intronic and intragenic regions in D. melanogaster and D. pseudoobscuraare followed by additional algorithm. The development of that algori […]


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