A computational tool that can help identifying SNPs associated with diseases, by focusing on SNPs affecting miRNA-regulation of genes. The tool predicts the effects of SNPs in miRNA target sites and uses linkage disequilibrium to map these miRNA-related variants to SNPs of interest in GWAS. Mirsnpscore provides computer-based predictions of SNP effects on microRNA-based gene regulation.
Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Interagon AS, Laboratoriesenteret, Trondheim, Norway; Department of Computer and Information Science, Norwegian University of Science and Technology, Trondheim, Norway
Mirsnpscore funding source(s)
Norwegian Research Council; Interagon AS; the Norwegian Functional Genomics Program (FUGE) of the Norwegian Research Council