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A computational tool that can help identifying SNPs associated with diseases, by focusing on SNPs affecting miRNA-regulation of genes. The tool predicts the effects of SNPs in miRNA target sites and uses linkage disequilibrium to map these miRNA-related variants to SNPs of interest in GWAS. Mirsnpscore provides computer-based predictions of SNP effects on microRNA-based gene regulation.

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Data access:
File download, Web user interface
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Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Interagon AS, Laboratoriesenteret, Trondheim, Norway; Department of Computer and Information Science, Norwegian University of Science and Technology, Trondheim, Norway

Funding source(s)

Norwegian Research Council; Interagon AS; the Norwegian Functional Genomics Program (FUGE) of the Norwegian Research Council

  • (Thomas et al., 2011) Inferring causative variants in microRNA target sites. Nucleic acids research.
    PMID: 21693556
  • Animals
    • Homo sapiens
    • Mus musculus
  • (Akhtar et al., 2016) Bioinformatic tools for microRNA dissection. Nucleic acids research.
    PMID: 26578605

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