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Provides an experimentally supported resource for microRNA (miRNA) sponges. We have established the experimentally supported miRSponge database that contains data on 599 miRNA-sponge interactions and 463 ceRNA relationships from 11 species following manual curating from nearly 1,200 published articles. Database classes include endogenously generated molecules including coding genes, pseudogenes, long non-coding RNAs and circular RNAs, along with exogenously introduced molecules including viral RNAs and artificial engineered sponges. Approximately 70% of the interactions were identified experimentally in disease states. miRSponge provides a user-friendly interface for convenient browsing, retrieval and downloading of dataset. A submission page is also included to allow researchers to submit newly validated miRNA sponge data.

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  • Shangwei Ning <ningsw at ems.hrbmu.edu.cn>


College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China

Funding source(s)

This work was supported in part by the National High Technology Research and Development Program of China [863 Program, 2014AA021102], the National Program on Key Basic Research Project [973 Program, 2014CB910504], the National Natural Science Foundation of China [91439117, 61473106 and 31401090], the Postdoctoral Science Foundation of China [2015M571432] and Postdoctoral Foundation of Heilongjiang Province [LBH-Z14148].

  • (Wang et al., 2015) miRSponge: a manually curated database for experimentally supported miRNA sponges and ceRNAs. Database.
    DOI: 10.1093/database/bav098
  • (Akhtar et al., 2016) Bioinformatic tools for microRNA dissection. Nucleic acids research.
    PMID: 26578605

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